Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | AQP1 | P29972 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.31 |
| ▸ | CCR6 | P51684 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1610320 | 1.00 | ALDH1A1 (0.33) | ALDH1A1SMN1; SMN2P2RX3HPGDMAPT | |
| SCHEMBL1609935 | 0.93 | SLC6A3 (0.35) | ALDH1A1SMN1; SMN2HPGDMAPTPTPN1 | |
| SCHEMBL1609934 | 0.93 | SLC6A3 (0.35) | ALDH1A1SMN1; SMN2HPGDMAPTPTPN1 | |
| SCHEMBL12713075 | 0.91 | NOS2 (0.33) | PTPN1 | |
| SCHEMBL1611472 | 0.91 | NOS2 (0.33) | PTPN1 | |
| SCHEMBL12713074 | 0.91 | PDE10A (0.35) | ALDH1A1SMN1; SMN2MAPTPTPN1PDE10A | |
| SCHEMBL1610312 | 0.91 | PDE10A (0.35) | ALDH1A1SMN1; SMN2MAPTPTPN1PDE10A | |
| SCHEMBL1610775 | 0.91 | PDE10A (0.35) | ALDH1A1SMN1; SMN2MAPTPTPN1PDE10A | |
| SCHEMBL1611867 | 0.86 | NPC1 (0.38) | SMN1; SMN2HPGDMAPTRAB9A | |
| SCHEMBL1611866 | 0.86 | NPC1 (0.38) | SMN1; SMN2HPGDMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | DDT, PNPO, CBR3 | ALDH1A1 1562/4885SMN1; SMN2 2654/4885P2RX3 566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.