SCHEMBL16119487

SCHEMBL16119487

CCCCOC(=O)N(C)CC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.52
ATM Q13315 1/20 0.48
TSHR P16473 5/20 0.45
HPGD P15428 2/20 0.45
CHRM2 P08172 1/20 0.43
CHRM4 P08173 1/20 0.43
CHRM5 P08912 1/20 0.43
CHRM1 P11229 1/20 0.43
CHRNB2 P17787 1/20 0.43
CHRM3 P20309 1/20 0.43
CHRNA4 P43681 1/20 0.43
DNM1 Q05193 1/20 0.43
HCAR2 Q8TDS4 1/20 0.42
NAAA Q02083 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ESR1 P03372 2/20 0.41
MAPK1 P28482 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
KDM4E B2RXH2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18125074 0.86 CHRNB2 (0.46) ALDH1A1TSHRCHRM2CHRM4CHRM5
SCHEMBL25565603 0.85 ALDH1A1 (0.50) ALDH1A1ATMTSHRHPGDCHRM2
SCHEMBL14138540 0.85 ALDH1A1 (0.50) ALDH1A1ATMTSHRHPGDCHRM2
SCHEMBL5044760 0.83 ALDH1A1 (0.48) ALDH1A1ATMTSHRHPGDCHRM2
SCHEMBL28439685 0.82 FAAH (0.49) MAPTLMNACYP1A2CYP2C19
SCHEMBL8908162 0.82 CHRNB2 (0.58) ALDH1A1ATMTSHRHPGDCHRM2
SCHEMBL24441009 0.82 CHRNB2 (0.39) ALDH1A1TSHRCHRM2CHRM4CHRM5
SCHEMBL2291415 0.82 ALDH1A1 (0.47) ALDH1A1ATMTSHRHPGDCHRM2
SCHEMBL1650042 0.82 CHRNB2 (0.57) ALDH1A1ATMTSHRHPGDCHRM2
SCHEMBL30195730 0.80 ALDH1A1 (0.45) ALDH1A1ATMTSHRHPGDCHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022100625-A1 NITROGEN-SUBSTITUTED AMINOCARBONATE THIOPHENE COMPOUND AND USE THEREOF 武汉人福创新药物研发中心有限公司 2022-05-19 WO disclosed
WO-2014151958-A1 BETA-LACTAMASE INHIBITORS VenatoRx Pharmaceuticals, Inc. (US) 2014-09-25 WO disclosed