Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 4/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 5/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PI4KA | P42356 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | RUNX1 | Q01196 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16121415 | 0.80 | TRPV1 (0.63) | NPBWR1TRPV1DGAT1PDE10ARUNX1 | |
| SCHEMBL16121162 | 0.78 | KDM4E (0.55) | NPBWR1TRPV1DGAT1PIK3CDPIK3CA | |
| SCHEMBL16121160 | 0.75 | KDM4E (0.45) | NPBWR1TRPV1DGAT1PIK3CDPIK3CA | |
| SCHEMBL16121405 | 0.74 | CHEK2 (0.47) | NPBWR1TRPV1DGAT1PIK3CDPIK3CA | |
| SCHEMBL16121404 | 0.74 | NPC1 (0.46) | NPBWR1DGAT1PDE10APIK3CDPIK3CA | |
| SCHEMBL16102119 | 0.72 | NPC1 (0.62) | DGAT1NPC1POLBNPSR1KCNH2 | |
| SCHEMBL24075264 | 0.68 | NPBWR1 (0.59) | NPBWR1TRPV1DGAT1KCNH2 | |
| SCHEMBL30278641 | 0.68 | DGAT1 (0.45) | NPBWR1TRPV1DGAT1NPC1KCNH2 | |
| SCHEMBL25168715 | 0.68 | DGAT1 (0.45) | NPBWR1TRPV1DGAT1NPC1KCNH2 | |
| SCHEMBL24168714 | 0.68 | NPBWR1 (0.40) | NPBWR1TRPV1DGAT1NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014149207-A2 | BENZIMIDAZOLE-BASED INSECTICIDAL COMPOSITIONS AND RELATED METHODS | DOW AGROSCIENCES LLC (US) | 2014-09-25 | — | — | WO | disclosed |