Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.44 |
| ▸ | RHEB | Q15382 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | PI4KA | P42356 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16121160 | 0.86 | KDM4E (0.45) | NPC1NPBWR1KDM4EALDH1A1TRPV1 | |
| SCHEMBL16121404 | 0.85 | NPC1 (0.46) | CHEK2NPC1NPBWR1RHEBKDM4E | |
| SCHEMBL16121162 | 0.82 | KDM4E (0.55) | NPC1NPBWR1KDM4EALDH1A1TRPV1 | |
| SCHEMBL900987 | 0.81 | RHEB (0.50) | CHEK2NPBWR1RHEBTRPV1DGAT1 | |
| SCHEMBL19137955 | 0.78 | TRPV1 (0.55) | CHEK2NPBWR1RHEBTRPV1DGAT1 | |
| SCHEMBL16102119 | 0.76 | NPC1 (0.62) | NPC1KDM4EALDH1A1RAB9ADGAT1 | |
| SCHEMBL16121161 | 0.75 | CBFB (0.58) | NPC1NPBWR1KDM4EALDH1A1DGAT1 | |
| SCHEMBL19137958 | 0.75 | DGAT1 (0.53) | CHEK2NPBWR1RHEBDGAT1KCNH2 | |
| SCHEMBL16121415 | 0.74 | TRPV1 (0.63) | CHEK2NPBWR1TRPV1DGAT1 | |
| SCHEMBL16121163 | 0.74 | NPBWR1 (0.41) | NPC1NPBWR1TRPV1DGAT1PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014149207-A2 | BENZIMIDAZOLE-BASED INSECTICIDAL COMPOSITIONS AND RELATED METHODS | DOW AGROSCIENCES LLC (US) | 2014-09-25 | — | — | WO | disclosed |