Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16122026 | 0.89 | SMN1; SMN2 (0.37) | CYP11B1CYP11B2ADORA1ADORA2AKDM5B | |
| SCHEMBL25513109 | 0.88 | PDE9A (0.37) | ADORA1KDM5BSMN1; SMN2HIF1AKDM4E | |
| SCHEMBL23263911 | 0.87 | ADORA1 (0.36) | CYP11B1CYP11B2ADORA1KDM5BSMN1; SMN2 | |
| SCHEMBL23348308 | 0.87 | KDM5B (0.34) | CYP11B1CYP11B2ADORA1ADORA2AKDM5B | |
| SCHEMBL22155947 | 0.87 | CYP11B1 (0.34) | CYP11B1CYP11B2ADORA1ADORA2AKDM5B | |
| SCHEMBL16122018 | 0.87 | CYP11B1 (0.42) | CYP11B1CYP11B2SMN1; SMN2HIF1AKDM4E | |
| SCHEMBL22155922 | 0.85 | PGR (0.39) | CYP11B1CYP11B2ADORA1ADORA2AKDM5B | |
| SCHEMBL22155927 | 0.84 | CYP11B1 (0.35) | CYP11B1CYP11B2ADORA1ADORA2AKDM5B | |
| SCHEMBL20596419 | 0.84 | PDE9A (0.38) | ADORA1KDM5BSMN1; SMN2HIF1AKDM4E | |
| SCHEMBL20279077 | 0.84 | ADORA1 (0.36) | CYP11B1CYP11B2ADORA1KDM5BSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2976322-B1 | SYNTHETIC BUILDING BLOCKS FOR THE PRODUCTION OF MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2019-11-20 | — | — | EP | disclosed |
| US-10407384-B2 | Synthetic building blocks for the production of materials for organic electroluminescence devices | MERCK PATENT GMBH (DE) | 2019-09-10 | — | — | US | disclosed |
| US-20170313650-A1 | SYNTHETIC BUILDING BLOCKS FOR THE PRODUCTION OF MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | UDC IRELAND LIMITED (IE) | 2017-11-02 | — | — | US | disclosed |
| US-9718764-B2 | Synthetic building blocks for the production of materials for organic electroluminescence devices | MERCK PATENT GMBH (DE) | 2017-08-01 | — | — | US | disclosed |
| US-20160046563-A1 | SYNTHETIC BUILDING BLOCKS FOR THE PRODUCTION OF MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | UDC IRELAND LIMITED (IE) | 2016-02-18 | — | — | US | disclosed |
| WO-2014146750-A1 | SYNTHETIC BUILDING BLOCKS FOR THE PRODUCTION OF MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2014-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160046563-A1 | SYNTHETIC BUILDING BLOCKS FOR THE PRODUCTION OF MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | TBCB, CYBA, BMP2 | CYP11B1 1641/4885CYP11B2 1484/4885ADORA1 4713/4885 |
| US-10407384-B2 | Synthetic building blocks for the production of materials for organic electroluminescence devices | TBCB, CYBA, BMP2 | CYP11B1 1641/4885CYP11B2 1484/4885ADORA1 4713/4885 |
| US-20170313650-A1 | SYNTHETIC BUILDING BLOCKS FOR THE PRODUCTION OF MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | TBCB, CYBA, BMP2 | CYP11B1 1641/4885CYP11B2 1484/4885ADORA1 4713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.