Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 6/20 | 0.42 |
| ▸ | CTSK | P43235 | 5/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14933160 | 1.00 | SMN1; SMN2 (0.46) | SMN1; SMN2ITGB3ITGA2BPPARGPPARA | |
| SCHEMBL18466600 | 0.90 | HDAC8 (0.44) | SMN1; SMN2ITGB3ITGA2BPPARGPPARA | |
| SCHEMBL18466602 | 0.89 | ITGB3 (0.43) | SMN1; SMN2ITGB3ITGA2BPPARGPPARA | |
| SCHEMBL28538646 | 0.88 | PPARG (0.47) | SMN1; SMN2ITGB3ITGA2BPPARGPPARA | |
| SCHEMBL16124224 | 0.88 | PPARG (0.47) | SMN1; SMN2ITGB3ITGA2BPPARGPPARA | |
| SCHEMBL16124245 | 0.84 | CTSS (0.58) | SMN1; SMN2ITGB3ITGA2BPPARACTSS | |
| SCHEMBL14582840 | 0.84 | CTSS (0.58) | SMN1; SMN2ITGB3ITGA2BPPARACTSS | |
| SCHEMBL7260079 | 0.83 | SMN1; SMN2 (0.48) | SMN1; SMN2ITGB3ITGA2BCTSSCTSK | |
| SCHEMBL30638149 | 0.83 | SMN1; SMN2 (0.48) | SMN1; SMN2ITGB3ITGA2BCTSSCTSK | |
| SCHEMBL13613759 | 0.82 | PLG (0.45) | ITGB3ITGA2BCTSSCTSKABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170204137-A1 | POLYETHYLENE GLYCOL BASED PRODRUG OF ADRENOMEDULLIN AND USE THEREOF | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-07-20 | — | — | US | disclosed |
| US-20140287984-A1 | POLYETHYLENE GLYCOL BASED PRODRUG OF ADRENOMEDULLIN AND USE THEREOF | Bayer Pharmaaktiengesellschaft (DE) | 2014-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140287984-A1 | POLYETHYLENE GLYCOL BASED PRODRUG OF ADRENOMEDULLIN AND USE THEREOF | TEK, MPEG1, PROKR1 | SMN1; SMN2 4516/4885ITGB3 2250/4885ITGA2B 3579/4885 |
| US-20170204137-A1 | POLYETHYLENE GLYCOL BASED PRODRUG OF ADRENOMEDULLIN AND USE THEREOF | TEK, MPEG1, PROKR1 | SMN1; SMN2 4516/4885ITGB3 2250/4885ITGA2B 3579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.