Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPRA | P18433 | 1/20 | 0.40 |
| ▸ | PTPRB | P23467 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL718627 | 0.85 | CYP1A2 (0.50) | CYP1A2 | |
| SCHEMBL9167412 | 0.85 | PTPN1 (0.39) | SMN1; SMN2HIF1AALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL338742 | 0.82 | SMN1; SMN2 (0.61) | SMN1; SMN2HIF1AALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL163162 | 0.80 | ALDH1A1 (0.54) | SMN1; SMN2HIF1AALDH1A1RECQLPTPN1 | |
| SCHEMBL21269769 | 0.80 | SMN1; SMN2 (0.59) | SMN1; SMN2HIF1AALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL21269594 | 0.80 | SMN1; SMN2 (0.59) | SMN1; SMN2HIF1AALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL21268824 | 0.80 | SMN1; SMN2 (0.59) | SMN1; SMN2HIF1AALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL395522 | 0.79 | SMN1; SMN2 (0.53) | SMN1; SMN2HIF1AALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL7434259 | 0.79 | SMN1; SMN2 (0.53) | SMN1; SMN2HIF1AALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL21269412 | 0.77 | SMN1; SMN2 (0.52) | SMN1; SMN2HIF1AALDH1A1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103188936-B | Insecticidal composition | DOW AGROSCIENCES LLC (US) | 2016-04-20 | — | — | CN | disclosed |
| US-8912338-B2 | Pesticidal compositions | Dow AgroScience, LLC. (US) | 2014-12-16 | — | — | US | disclosed |
| US-8912338-B2 | Pesticidal compositions | Dow AgroScience, LLC. (US) | 2014-12-16 | — | — | US | disclosed |
| US-8912338-B2 | Pesticidal compositions | Dow AgroScience, LLC. (US) | 2014-12-16 | — | — | US | disclosed |
| US-20140057785-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2014-02-27 | — | — | US | disclosed |
| US-20140057785-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2014-02-27 | — | — | US | disclosed |
| US-20140057785-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2014-02-27 | — | — | US | disclosed |
| EP-2611299-A1 | PESTICIDAL COMPOSITIONS | Dow AgroSciences LLC (US) | 2013-07-10 | — | — | EP | disclosed |
| CN-103188936-A | Insecticidal composition | DOW AGROSCIENCES LLC | 2013-07-03 | — | — | CN | disclosed |
| WO-2012030681-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2012-03-08 | — | — | WO | disclosed |
| WO-2012030681-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2012-03-08 | — | — | WO | disclosed |
| US-20120053146-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC | 2012-03-01 | — | — | US | disclosed |
| US-20120053146-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053146-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PTMS | SMN1; SMN2 3552/4885HIF1A 4811/4885ALDH1A1 1882/4885 |
| US-20140057785-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PTMS | SMN1; SMN2 4175/4885HIF1A 4823/4885ALDH1A1 1438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.