Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17563223 | 0.89 | SLC1A3 (0.50) | IKBKBBRD4SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL29656838 | 0.79 | IKBKB (0.46) | IKBKBBRD4SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL19051065 | 0.75 | L3MBTL1 (0.40) | DHODH | |
| SCHEMBL16127491 | 0.74 | IKBKB (0.53) | IKBKBBRD4MAPTCNR2AKR1C3 | |
| SCHEMBL19051067 | 0.73 | L3MBTL1 (0.39) | DHODH | |
| SCHEMBL29678302 | 0.73 | TSHR (0.58) | PGRALDH1A1IDO1NOTUMASIC3 | |
| SCHEMBL1263144 | 0.73 | TSHR (0.58) | PGRALDH1A1IDO1NOTUMASIC3 | |
| SCHEMBL27457030 | 0.73 | ACHE (0.45) | CNR2AKR1C3AKR1C2NR3C1ALDH1A1 | |
| SCHEMBL19051075 | 0.72 | DHODH (0.34) | DHODH | |
| SCHEMBL23056293 | 0.72 | AKR1C3 (0.46) | IKBKBBRD4SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014146752-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2014-09-25 | — | — | WO | disclosed |