Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10285142 | 1.00 | TSHR (0.35) | TSHRFDPSKDM4ESLC22A1ALDH1A1 | |
| SCHEMBL2565949 | 0.87 | FDPS (0.33) | FDPSKDM4ESLC22A1ALDH1A1CYP1A2 | |
| SCHEMBL19889381 | 0.86 | FDPS (0.34) | TSHRFDPSBCHECYP2D6HSP90AA1 | |
| SCHEMBL5949130 | 0.82 | DNM1 (0.38) | TSHRFDPSALDH1A1OPRM1 | |
| SCHEMBL2565897 | 0.81 | OPRM1 (0.33) | FDPSKDM4ESLC22A1ALDH1A1CYP1A2 | |
| SCHEMBL2565496 | 0.81 | FDPS (0.31) | FDPSKDM4ESLC22A1ALDH1A1CYP1A2 | |
| SCHEMBL5948784 | 0.80 | OPRM1 (0.46) | OPRM1 | |
| SCHEMBL9949348 | 0.80 | TSHR (0.37) | TSHRALDH1A1HSP90AA1HSP90AB1 | |
| SCHEMBL11446973 | 0.80 | HSP90AA1 (0.32) | HSP90AA1HSP90AB1 | |
| SCHEMBL20344865 | 0.79 | FDPS (0.37) | TSHRFDPSBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118772063-B | Tetrahydropyridazines method for synthesizing compound | 西北师范大学 | 2025-06-13 | — | — | CN | claimed |
| CN-120082045-A | Polymer elastomer and preparation method and application thereof | 沧州旭阳化工有限公司 | 2025-06-03 | — | — | CN | claimed |
| CN-119954837-A | Organic luminescent material with chiral and narrow band emission properties as well as preparation method and application thereof | 杭州师范大学 | 2025-05-09 | — | — | CN | claimed |
| CN-118772063-A | Tetrahydropyridazines method for synthesizing compound | 西北师范大学 | 2024-10-15 | — | — | CN | claimed |
| CN-1253546-C | Serial cleaning agent for removing gum stain | RADIOLOGY RES INST CHINESE ACA (CN) | 2006-04-26 | — | — | CN | claimed |
| CN-118772063-B | Tetrahydropyridazines method for synthesizing compound | 西北师范大学 | 2025-06-13 | — | — | CN | disclosed |
| CN-120082045-A | Polymer elastomer and preparation method and application thereof | 沧州旭阳化工有限公司 | 2025-06-03 | — | — | CN | disclosed |
| CN-119954837-A | Organic luminescent material with chiral and narrow band emission properties as well as preparation method and application thereof | 杭州师范大学 | 2025-05-09 | — | — | CN | disclosed |
| CN-119176786-A | Double chiral center thiazolidineone derivative and preparation method and application thereof | 上海体育大学 | 2024-12-24 | — | — | CN | disclosed |
| EP-4466262-A1 | DEGRADATION OF (EGFR) BY CONJUGATION OF EGFR INHIBITORS WITH E3 LIGASE LIGAND AND METHODS OF USE | BeiGene, Ltd. (KY) | 2024-11-27 | — | — | EP | disclosed |
| US-20240368203-A1 | DEGRADATION OF (EGFR) BY CONJUGATION OF EGFR INHIBITORS WITH E3 LIGASE LIGAND AND METHODS OF USE | BEIGENE, LTD. (KY) | 2024-11-07 | — | — | US | disclosed |
| US-20240342292-A1 | Compounds for the Degradation of EGFR Kinase | BEIGENE SWITZERLAND GMBH (CH) | 2024-10-17 | — | — | US | disclosed |
| WO-2001090112-A1 | CHEMICAL PRODUCTS SUITED FOR USE AS CO-CATALYSTS, METHOD FOR THE PREPARATION THEREOF AND THEIR USE IN CATALYST SYSTEMS FOR PRODUCING POLYOLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2001-11-29 | — | — | WO | disclosed |
| US-6319469-B1 | MICROSYSTEM; PLATFORM, SUBSTRATE WITH EMBEDDED REACTION CHAMBERS AND CHANNELS CONNECTED TO MICROVALVE AND VENTED THEREBY, FLUID FLOW CONTROLLED; MICROMANIPULATION DEVICE INTERFACE; MICROANALYSES AND MICROSYNTHESIS | SILICON VALLEY BANK | 2001-11-20 | — | — | US | disclosed |
| WO-2001047635-A2 | SUPPORTED CATALYST SYSTEM CONTAINING A METALLOCENE, A LEWIS BASE AND AN ELEMENTALLY ORGANIC COMPOUND OF MAIN GROUP III AND THE USE THEREOF | BASELL POLYPROPYLEN GMBH (DE) | 2001-07-05 | — | — | WO | disclosed |
| WO-2001048035-A2 | CHEMICAL COMPOUND, METHOD FOR THE PRODUCTION THEREOF AND ITS USE IN CATALYST SYSTEMS FOR PRODUCING POLYOLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2001-07-05 | — | — | WO | disclosed |
| US-5871572-A | COLORANT, WATER, A WATER-SOLUBLE ORGANIC SOLVENT, AND PECTIC ACID | SEIKO EPSON CORPORATION (JP) | 1999-02-16 | — | — | US | disclosed |
| EP-0865606-A1 | DEVICES AND METHODS FOR USING CENTRIPETAL ACCELERATION TO DRIVE FLUID MOVEMENT IN A MICROFLUIDICS SYSTEM WITH ON-BOARD INFORMATICS | Gamera Bioscience Corporation (US) | 1998-09-23 | — | — | EP | disclosed |
| EP-0838508-A2 | Aqueous ink composition for use in an ink-jet printer | SEIKO EPSON CORPORATION (JP) | 1998-04-29 | — | — | EP | disclosed |
| WO-1997021090-A1 | DEVICES AND METHODS FOR USING CENTRIPETAL ACCELERATION TO DRIVE FLUID MOVEMENT IN A MICROFLUIDICS SYSTEM WITH ON-BOARD INFORMATICS | GAMERA BIOSCIENCE (US) | 1997-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240368203-A1 | DEGRADATION OF (EGFR) BY CONJUGATION OF EGFR INHIBITORS WITH E3 LIGASE LIGAND AND METHODS OF USE | EGFR, CBL, ERBB2 | TSHR 2105/4885FDPS 4346/4885KDM4E 1783/4885 |
| US-20240342292-A1 | Compounds for the Degradation of EGFR Kinase | EGFR, ERBB2, ERBB3 | TSHR 2376/4885FDPS 3846/4885KDM4E 1776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.