Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 5/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
| ▸ | SPR | P35270 | 3/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | ABAT | P80404 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16129765 | 0.94 | PDK1 (0.41) | TACR1PDK1PDK2PDK3PDK4 | |
| SCHEMBL16129777 | 0.91 | TACR1 (0.41) | TACR1PDK1PDK2PDK3PDK4 | |
| SCHEMBL16129771 | 0.90 | TACR1 (0.42) | TACR1PDK1PDK2PDK3PDK4 | |
| SCHEMBL16129897 | 0.88 | TACR1 (0.47) | TACR1STSGPR119ENPP2 | |
| SCHEMBL16129776 | 0.85 | TACR1 (0.41) | TACR1STSSPRGPR119HTR2A | |
| SCHEMBL16129773 | 0.85 | TACR1 (0.40) | TACR1STSGPR119HTR2AABAT | |
| SCHEMBL16129851 | 0.85 | ENPP2 (0.36) | TACR1HTR2AABATENPP2SIGMAR1 | |
| SCHEMBL16129761 | 0.83 | F2RL1 (0.43) | TACR1STSSPRGPR119HTR2A | |
| SCHEMBL16129775 | 0.83 | ENPP2 (0.45) | TACR1STSGPR119ENPP2 | |
| SCHEMBL16129891 | 0.82 | ENPP2 (0.39) | TACR1PDK1PDK2HTR2AABAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014152725-A1 | S1P AND/OR ATX MODULATING AGENTS | BIOGEN IDEC MA INC. (US) | 2014-09-25 | — | — | WO | disclosed |