Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.43 |
| ▸ | GRM5 | P41594 | 8/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 5/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16099598 | 0.93 | PTGDR2 (0.44) | PTGDR2GRM5TMEM97SIGMAR1DPP4 | |
| SCHEMBL16100169 | 0.91 | PTGDR2 (0.42) | PTGDR2GRM5TMEM97SIGMAR1 | |
| SCHEMBL16099812 | 0.83 | GRM5 (0.40) | PTGDR2GRM5TMEM97SIGMAR1DPP4 | |
| SCHEMBL16099497 | 0.79 | TACR1 (0.39) | SIGMAR1 | |
| SCHEMBL16100641 | 0.79 | FAAH (0.45) | PTGDR2GRM5 | |
| SCHEMBL16100107 | 0.79 | GRM5 (0.36) | PTGDR2GRM5TMEM97SIGMAR1DPP4 | |
| SCHEMBL16099399 | 0.78 | RAB9A (0.33) | PTGDR2GRM5TMEM97SIGMAR1 | |
| SCHEMBL16093646 | 0.77 | ENPP2 (0.40) | PTGDR2GRM5SIGMAR1 | |
| SCHEMBL16099642 | 0.76 | TACR1 (0.39) | SIGMAR1 | |
| SCHEMBL16103128 | 0.76 | GRM5 (0.36) | PTGDR2GRM5TMEM97SIGMAR1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014152725-A1 | S1P AND/OR ATX MODULATING AGENTS | BIOGEN IDEC MA INC. (US) | 2014-09-25 | — | — | WO | disclosed |