Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16130292 | 1.00 | LMNA (0.32) | LMNAHIF1AEPAS1ALDH1A1CNR1 | |
| SCHEMBL13864242 | 0.86 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL26740644 | 0.83 | — | — | |
| SCHEMBL16130800 | 0.80 | PIK3CD (0.35) | LMNAHIF1AEPAS1 | |
| SCHEMBL16130809 | 0.80 | ALDH1A1 (0.42) | ALDH1A1CNR1CNR2 | |
| SCHEMBL19771019 | 0.77 | — | — | |
| SCHEMBL128395 | 0.76 | LMNA (0.41) | LMNAALDH1A1 | |
| SCHEMBL16902072 | 0.75 | LPAR2 (0.34) | ALDH1A1 | |
| SCHEMBL12863334 | 0.75 | — | — | |
| SCHEMBL13864109 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8846638-B2 | Macrocyclic nucleoside phosphoramidate derivatives | ENANTA PHARMACEUTICALS, INC. (US) | 2014-09-30 | — | — | US | disclosed |