Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.40 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
| ▸ | F3 | P13726 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26740644 | 0.85 | — | — | |
| SCHEMBL16902067 | 0.83 | ALDH1A1 (0.56) | ALDH1A1CNR1CNR2LPAR3LPAR2 | |
| SCHEMBL11856338 | 0.83 | ALDH1A1 (0.56) | ALDH1A1CNR1CNR2LPAR3LPAR2 | |
| SCHEMBL18134817 | 0.83 | ALDH1A1 (0.56) | ALDH1A1CNR1CNR2LPAR3LPAR2 | |
| SCHEMBL11856333 | 0.83 | ALDH1A1 (0.56) | ALDH1A1CNR1CNR2LPAR3LPAR2 | |
| SCHEMBL16902064 | 0.81 | LPAR2 (0.34) | ALDH1A1LPAR3LPAR2LPAR1 | |
| SCHEMBL16902072 | 0.81 | LPAR2 (0.34) | ALDH1A1LPAR3LPAR2LPAR1 | |
| SCHEMBL16130292 | 0.80 | LMNA (0.32) | ALDH1A1CNR1CNR2 | |
| SCHEMBL16130397 | 0.80 | LMNA (0.32) | ALDH1A1CNR1CNR2 | |
| SCHEMBL28734332 | 0.79 | LPAR2 (0.43) | ALDH1A1CNR1CNR2LPAR3LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8846638-B2 | Macrocyclic nucleoside phosphoramidate derivatives | ENANTA PHARMACEUTICALS, INC. (US) | 2014-09-30 | — | — | US | disclosed |