Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.69 |
| ▸ | MEN1 | O00255 | 6/20 | 0.69 |
| ▸ | MAPT | P10636 | 6/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.69 |
| ▸ | TTR | P02766 | 4/20 | 0.69 |
| ▸ | LMNA | P02545 | 4/20 | 0.69 |
| ▸ | TP53 | P04637 | 4/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.69 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.60 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.56 |
| ▸ | TUBB | P07437 | 2/20 | 0.56 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.56 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.56 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.56 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.56 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.56 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.56 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.56 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1808387 | 0.91 | MEN1 (0.84) | KDM4EMEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL1808386 | 0.91 | MEN1 (0.84) | KDM4EMEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL2574065 | 0.88 | LMNA (0.77) | KDM4EMEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL2574064 | 0.88 | LMNA (0.77) | KDM4EMEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL1486831 | 0.84 | MEN1 (0.73) | KDM4EMEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL1486827 | 0.84 | MEN1 (0.73) | KDM4EMEN1MAPTKMT2ACYP3A4 | |
| Triacetylresveratrol SCHEMBL717980 | 0.82 | TTR (1.00) | KDM4EMEN1MAPTKMT2ACYP3A4 | |
| Triacetylresveratrol SCHEMBL717979 | 0.82 | TTR (1.00) | KDM4EMEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL18471992 | 0.82 | LMNA (0.69) | KDM4EMEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL15686516 | 0.81 | PTGS2 (0.68) | KDM4EMEN1MAPTKMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8846724-B2 | Compositions for treating obesity and insulin resistance disorders | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-09-30 | — | — | US | disclosed |