SCHEMBL2574064

SCHEMBL2574064

CC(=O)Oc1ccc(/C=C/c2cc(O)cc(O)c2)cc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 5/20 0.77
▸ MAPT P10636 5/20 0.77
▸ KDM4E B2RXH2 4/20 0.77
▸ MEN1 O00255 4/20 0.77
▸ KMT2A Q03164 4/20 0.77
▸ TP53 P04637 3/20 0.77
▸ CYP3A4 P08684 3/20 0.77
▸ SMN1; SMN2 Q16637 3/20 0.77
▸ TTR P02766 3/20 0.77
▸ TUBB4A P04350 2/20 0.65
▸ TUBB P07437 2/20 0.65
▸ TUBA3C P0DPH7 2/20 0.65
▸ TUBA1B P68363 2/20 0.65
▸ TUBA4A P68366 2/20 0.65
▸ TUBB4B P68371 2/20 0.65
▸ TUBB3 Q13509 2/20 0.65
▸ TUBB2A Q13885 2/20 0.65
▸ TUBB8 Q3ZCM7 2/20 0.65
▸ TUBA3E Q6PEY2 2/20 0.65
▸ TUBA1A Q71U36 2/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2574065 1.00 LMNA (0.77) LMNAMAPTKDM4EMEN1KMT2A
SCHEMBL1808387 0.93 MEN1 (0.84) LMNAMAPTKDM4EMEN1KMT2A
SCHEMBL1808386 0.93 MEN1 (0.84) LMNAMAPTKDM4EMEN1KMT2A
SCHEMBL18471992 0.90 LMNA (0.69) LMNAMAPTKDM4EMEN1KMT2A
SCHEMBL3688258 0.89 KDM4E (0.67) LMNAMAPTKDM4EMEN1KMT2A
SCHEMBL3688259 0.89 KDM4E (0.67) LMNAMAPTKDM4EMEN1KMT2A
SCHEMBL10941162 0.89 MAPT (0.81) LMNAMAPTKDM4EMEN1KMT2A
SCHEMBL2451780 0.89 MAPT (0.81) LMNAMAPTKDM4EMEN1KMT2A
SCHEMBL11354408 0.89 MAPT (0.81) LMNAMAPTKDM4EMEN1KMT2A
SCHEMBL16130494 0.88 KDM4E (0.69) LMNAMAPTKDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060014705-A1 Compositions and methods for selectively activating human sirtuins BIOMOL INTERNATIONAL, INC. 2006-01-19 — — US claimed
CN-119454487-A Preparation method and application of resveratrol and derivative thereof 上海相宜本草化妆品股份有限公司 2025-02-18 — — CN disclosed
US-12029706-B2 Methods for treating mucopolysaccharidosis UNIVERSITY OF MIAMI (US) 2024-07-09 — — US disclosed
US-12029706-B2 Methods for treating mucopolysaccharidosis UNIVERSITY OF MIAMI (US) 2024-07-09 — — US disclosed
EP-3280402-B1 TOLAN COMPOUNDS FOR PROMOTING WOUND HEALING BIOMENDICS LLC (US) 2024-06-05 — — EP disclosed
WO-2023150072-A1 COMPOSITIONS AND METHODS FOR THE PRESERVATION OF PLANT MATTER SINCLAIR DAVID A (US) 2023-08-10 — — WO disclosed
US-11419841-B2 Uses of lipophenolic compounds UNIVERSITE DE MONTPELLIER 2022-08-23 — — US disclosed
EP-3134421-B1 NEW LIPOPHENOL COMPOUNDS AND USES THEREOF INST NAT SANTE RECH MED (FR) 2022-04-20 — — EP disclosed
EP-3134421-B1 NEW LIPOPHENOL COMPOUNDS AND USES THEREOF INST NAT SANTE RECH MED (FR) 2022-04-20 — — EP disclosed
US-11185514-B2 Aqueous solution comprising a polyphenol OPTERION HEALTH AG (CH) 2021-11-30 — — US disclosed
US-7544497-B2 Compositions for manipulating the lifespan and stress response of cells and organisms PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2009-06-09 — — US disclosed
US-20090099137-A1 Anti-Inflammatory Compounds and Uses Thereof MEDICON PHARMACEUTICALS, INC. 2009-04-16 — — US disclosed
US-20090099137-A1 Anti-Inflammatory Compounds and Uses Thereof MEDICON PHARMACEUTICALS, INC. 2009-04-16 — — US disclosed
WO-2009012551-A1 RESVERATROL COMPLEX AND PROCESS FOR THE PREPERATION UNIÄO BRASILEIRA DE EDUCAÇAO E ASSITENCIA-MANTENEDORA DA PUCRS (BR) 2009-01-29 — — WO disclosed
US-20090012130-A1 Strategies for Designing Drugs that Target the Sir2 Family of Enzymes THE JOHNS HOPKINS UNIVERSITY (US) 2009-01-08 — — US disclosed
US-20080255382-A1 N-heterocyclic carbon-type ligand coupling in the presence of a base with benzyol halide and styrene coupling partners; resveratrol; increased stability for use in the food, cosmetic and pharmaceutical industries BRIGHAM YOUNG UNIVERSITY 2008-10-16 — — US disclosed
US-20080255382-A1 N-heterocyclic carbon-type ligand coupling in the presence of a base with benzyol halide and styrene coupling partners; resveratrol; increased stability for use in the food, cosmetic and pharmaceutical industries BRIGHAM YOUNG UNIVERSITY 2008-10-16 — — US disclosed
US-20080255382-A1 N-heterocyclic carbon-type ligand coupling in the presence of a base with benzyol halide and styrene coupling partners; resveratrol; increased stability for use in the food, cosmetic and pharmaceutical industries BRIGHAM YOUNG UNIVERSITY 2008-10-16 — — US disclosed
US-20060084135-A1 Compositions for manipulating the lifespan and stress response of cells and organisms BIOMOL INTERNATIONAL, INC. 2006-04-20 — — US disclosed
US-20060014705-A1 Compositions and methods for selectively activating human sirtuins BIOMOL INTERNATIONAL, INC. 2006-01-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090099137-A1 Anti-Inflammatory Compounds and Uses Thereof TNF, NFKBIA, IL6 LMNA 1744/4885MAPT 392/4885KDM4E 4668/4885
US-11185514-B2 Aqueous solution comprising a polyphenol SORD, SI, AQP1 LMNA 3193/4885MAPT 362/4885KDM4E 2998/4885
US-12029706-B2 Methods for treating mucopolysaccharidosis GAA, MAN2B1, IDUA LMNA 567/4885MAPT 4009/4885KDM4E 3519/4885
US-20060014705-A1 Compositions and methods for selectively activating human sirtuins SIRT1, SIRT7, SIRT5 LMNA 1010/4885MAPT 3039/4885KDM4E 640/4885
US-11419841-B2 Uses of lipophenolic compounds MALT1, LIPG, CCR1 LMNA 3017/4885MAPT 4652/4885KDM4E 3919/4885
US-20080255382-A1 N-heterocyclic carbon-type ligand coupling in the presence of a base with benzyol halide and styrene coupling partners; resveratrol; increased stability for use in the food, cosmetic and pharmaceutical industries RB1, SBK1, NADK LMNA 1421/4885MAPT 4496/4885KDM4E 1793/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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