Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 3/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1610833 | 0.88 | CFTR (0.32) | CFTRALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL1609769 | 0.86 | CFTR (0.33) | CFTRRAB9ANPC1POLBCACNA1B | |
| SCHEMBL1609528 | 0.84 | ALPL (0.37) | CFTRALPLRAB9ANPC1ALDH1A1 | |
| SCHEMBL1610843 | 0.82 | CFTR (0.41) | CFTRRAB9ANPC1POLBKDM4E | |
| SCHEMBL1612741 | 0.82 | TUBB4A (0.36) | RAB9ANPC1POLBALDH1A1KDM4E | |
| SCHEMBL27856129 | 0.82 | KDM4E (0.39) | RAB9ANPC1POLBALDH1A1KDM4E | |
| SCHEMBL11903207 | 0.81 | HSD17B10 (0.36) | CFTRRAB9ANPC1POLBCACNA1B | |
| SCHEMBL1609021 | 0.81 | ALDH1A1 (0.42) | RAB9ANPC1ALDH1A1KDM4EHPGD | |
| SCHEMBL1610593 | 0.80 | TUBB4A (0.41) | RAB9ANPC1POLBALDH1A1KDM4E | |
| SCHEMBL1610481 | 0.80 | CFTR (0.38) | CFTRRAB9ANPC1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | DDT, PNPO, CBR3 | CFTR 3623/4885ALPL 1756/4885ACLY 905/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.