SCHEMBL1613317

SCHEMBL1613317

O=C(O)C(S)c1ccc2ccccc2n1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.50
KDM4E B2RXH2 3/20 0.47
PRNP P04156 3/20 0.47
RXFP1 Q9HBX9 3/20 0.47
ALDH1A1 P00352 3/20 0.47
MAPK10 P53779 2/20 0.47
NPSR1 Q6W5P4 2/20 0.47
CNR2 P34972 2/20 0.46
LMNA P02545 1/20 0.44
RAB9A P51151 3/20 0.42
NPC1 O15118 2/20 0.42
NFKB1 P19838 1/20 0.42
NFKB2 Q00653 1/20 0.42
RELA Q04206 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
HSD17B10 Q99714 1/20 0.42
CYP1A2 P05177 1/20 0.41
KMT2A Q03164 1/20 0.41
GAA P10253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7774729 0.80 MGAM (0.52) MGAMKDM4EPRNPRXFP1ALDH1A1
SCHEMBL27325063 0.79 MGAM (0.50) MGAMKDM4EPRNPRXFP1ALDH1A1
SCHEMBL27721065 0.79 MGAM (0.50) MGAMKDM4EPRNPRXFP1ALDH1A1
SCHEMBL3673078 0.79 KDM4E (0.55) MGAMKDM4EPRNPRXFP1ALDH1A1
SCHEMBL27519044 0.79 KDM4E (0.51) MGAMKDM4EPRNPRXFP1ALDH1A1
SCHEMBL2310345 0.78 ALDH1A1 (0.48) MGAMKDM4EPRNPRXFP1ALDH1A1
Anthracene SCHEMBL10416586 0.77 MGAM (0.49) MGAMKDM4EPRNPRXFP1ALDH1A1
SCHEMBL4289764 0.77 MGAM (0.49) MGAMKDM4EPRNPRXFP1ALDH1A1
SCHEMBL9870690 0.74 MGAM (0.48) MGAMKDM4EPRNPRXFP1ALDH1A1
SCHEMBL16294922 0.73 MGAM (0.45) MGAMKDM4EPRNPRXFP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118439998-A Preparation and application of quinoline thioglycollic acid sulfonamide derivative 江苏正大清江制药有限公司 2024-08-06 CN claimed
CN-115385854-B Preparation and application of quinoline thioglycollic acid sulfonamide derivative 江苏正大清江制药有限公司 2024-04-09 CN claimed
US-20080108115-A1 ENHANCED PRODUCTION OF TAXOL AND TAXANES BY CELL CULTURES OF TAXUS SPECIES DFB BIOTECH, INCORPORATED (US) 2008-05-08 US claimed
US-7264951-B1 Enhanced production of taxol and taxanes by cell cultures of Taxus species PHYTON, INC. (US) 2007-09-04 US claimed
CN-121895228-A Industrial production method of quinoline thioglycollic acid sulfonamide compound 江苏正大清江制药有限公司 2026-04-21 CN disclosed
CN-121895228-A Industrial production method of quinoline thioglycollic acid sulfonamide compound 江苏正大清江制药有限公司 2026-04-21 CN disclosed
CN-118439998-A Preparation and application of quinoline thioglycollic acid sulfonamide derivative 江苏正大清江制药有限公司 2024-08-06 CN disclosed
CN-118439998-A Preparation and application of quinoline thioglycollic acid sulfonamide derivative 江苏正大清江制药有限公司 2024-08-06 CN disclosed
CN-118439998-A Preparation and application of quinoline thioglycollic acid sulfonamide derivative 江苏正大清江制药有限公司 2024-08-06 CN disclosed
CN-115385854-B Preparation and application of quinoline thioglycollic acid sulfonamide derivative 江苏正大清江制药有限公司 2024-04-09 CN disclosed
CN-115385854-B Preparation and application of quinoline thioglycollic acid sulfonamide derivative 江苏正大清江制药有限公司 2024-04-09 CN disclosed
CN-115385854-B Preparation and application of quinoline thioglycollic acid sulfonamide derivative 江苏正大清江制药有限公司 2024-04-09 CN disclosed
EP-1538214-A1 Enhanced production of taxanes by cell cultures of taxus species PHYTON, INC. (US) 2005-06-08 EP disclosed
EP-1398384-A1 Enhanced production of taxanes by cell cultures of taxus species Phyton Inc. (US) 2004-03-17 EP disclosed
EP-0954596-A1 ENHANCED PRODUCTION OF TAXANES BY CELL CULTURES OF $i(TAXUS) SPECIES PHYTON, INC. (US) 1999-11-10 EP disclosed
WO-1997044476-A1 ENHANCED PRODUCTION OF TAXANES BY CELL CULTURES OF TAXUS SPECIES PHYTON, INC. (US) 1997-11-27 WO disclosed
EP-0067352-B2 PROCESS FOR PREPARING S-ARYL-THIOGLYCOLIC ACIDS BAYER AG (DE) 1988-01-13 EP disclosed
EP-0067352-B1 PROCESS FOR PREPARING S-ARYL-THIOGLYCOLIC ACIDS BAYER AG (DE) 1984-08-15 EP disclosed
US-4461911-A FROM THIOGLYCOLIC ACID AND AN ARYLDIAZONIUM SALT, COPPER SALT, ACID MEDIUM BAYER AKTIENGESELLSCHAFT (DE) 1984-07-24 US disclosed
EP-0067352-A1 Process for preparing S-aryl-thioglycolic acids BAYER AG (DE) 1982-12-22 EP disclosed