SCHEMBL161333

SCHEMBL161333

OC1CCC(SC2CCC(O)CC2)CC1

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.41
EPHX2 P34913 1/20 0.33
SHBG P04278 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2813662 0.80
SCHEMBL24009290 0.79 TSHR (0.41) TSHREPHX2SHBG
SCHEMBL10789621 0.79 TSHR (0.41) TSHREPHX2SHBG
SCHEMBL24837527 0.79 TSHR (0.41) TSHREPHX2SHBG
SCHEMBL805191 0.78 SHBG (0.35) SHBG
SCHEMBL2700308 0.76 TSHR (0.64) TSHREPHX2SHBG
SCHEMBL28182 0.76
SCHEMBL3389566 0.76 TSHR (0.64) TSHREPHX2SHBG
SCHEMBL102859 0.76
SCHEMBL1593359 0.76 TSHR (0.64) TSHREPHX2SHBG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 284 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4526921-A Acetal resin, low molecular weight polycarbonate MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1985-07-02 US claimed
US-4477652-A Condensation polymers of cyclic diols with aldehydes or acetals of aldehydes PHILLIPS PETROLEUM COMPANY (US) 1984-10-16 US claimed
US-12570870-B2 Curable compositions, abrasion-resistant articles, and method of thermoforming the same 3M INNOVATIVE PROPERTIES COMPANY (US) 2026-03-10 US disclosed
CN-119350709-A Nucleating agent composition, olefin resin composition, molded article thereof, and process for producing olefin resin composition 株式会社ADEKA 2025-01-24 CN disclosed
US-12173178-B2 Polyfunctional hydrazide crosslinker PPG INDUSTRIES OHIO, INC. (US) 2024-12-24 US disclosed
CN-113330058-B Nucleating agent composition, olefin resin composition, molded article thereof, and process for producing olefin resin composition 株式会社ADEKA 2024-10-11 CN disclosed
US-20240117215-A1 POLYFUNCTIONAL HYDRAZIDE CROSSLINKER PPG INDUSTRIES OHIO, INC. (US) 2024-04-11 US disclosed
US-20230365737-A1 ISO(THIO)CYANATE COMPOUND, POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL, MOLDED BODY, OPTICAL MATERIAL, PLASTIC LENS, PLASTIC POLARIZING LENS, METHOD FOR PRODUCING ISO(THIO)CYANATE COMPOUND, METHOD FOR PRODUCING POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL, METHOD FOR PRODUCING OPTICAL MATERIAL, AND METHOD FOR PRODUCING PLASTIC POLARIZING LENS MITSUI CHEMICALS, INC. (JP) 2023-11-16 US disclosed
EP-4259678-A1 POLYFUNCTIONAL HYDRAZIDE CROSSLINKER PPG Industries Ohio Inc. (US) 2023-10-18 EP disclosed
US-20230272188-A1 ADDITIVE COMPOSITION, RESIN COMPOSITION CONTAINING SAME, AND MOLDED ARTICLE OF SAID RESIN COMPOSITION ADEKA CORPORATION (JP) 2023-08-31 US disclosed
US-20230220219-A1 COMPOSITIONS CONTAINING THERMALLY CONDUCTIVE FILLERS PPG INDUSTRIES OHIO, INC. (US) 2023-07-13 US disclosed
EP-0422836-B1 Resin for urethane lenses, lenses comprising the resin, and a process for preparation of the resin and the lenses MITSUI TOATSU CHEMICALS (JP) 1994-08-24 EP disclosed
US-5059673-A bis(isocyanatomethyl)-norbornane or -4,7methonohexahydroindan e high refractive index, lightweight, high impact MITSUI TOATSU CHEMICALS, INC. (JP) 1991-10-22 US disclosed
EP-0422836-A2 Resin for urethane lenses, lenses comprising the resin, and a process for preparation of the resin and the lenses MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-04-17 EP disclosed
US-4956425-A HIGH IMPACT STRENGTH COATINGS FOR PROTECTIVE COATINGS THE DOW CHEMICAL COMPANY (US) 1990-09-11 US disclosed
US-4835228-A EPOXY RESINS, VINYLAROMATIC, HYDROXYALKYL ACRYLATE THE DOW CHEMICAL COMPANY (US) 1989-05-30 US disclosed
US-4526921-A Acetal resin, low molecular weight polycarbonate MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1985-07-02 US disclosed
US-4477652-A Condensation polymers of cyclic diols with aldehydes or acetals of aldehydes PHILLIPS PETROLEUM COMPANY (US) 1984-10-16 US disclosed
US-4065433-A Process for the manufacture of polyaddition products containing imide groups CIBA-GEIGY CORPORATION (US) 1977-12-27 US disclosed
US-4046777-A INTERMEDIATES FOR HEAT-RESISTANT POLYMERS CIBA-GEIGY CORPORATION (US) 1977-09-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12570870-B2 Curable compositions, abrasion-resistant articles, and method of thermoforming the same VCL, LBR, ACR TSHR 927/4885EPHX2 4401/4885SHBG 3437/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.