Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16774821 | 0.86 | TSHR (0.46) | TSHR | |
| SCHEMBL15044046 | 0.83 | TSHR (0.31) | TSHR | |
| SCHEMBL28313699 | 0.82 | TSHR (0.42) | TSHR | |
| SCHEMBL28275286 | 0.82 | TSHR (0.42) | TSHR | |
| SCHEMBL29011322 | 0.80 | TSHR (0.41) | TSHR | |
| SCHEMBL7248980 | 0.80 | TSHR (0.50) | TSHR | |
| SCHEMBL28288684 | 0.79 | TSHR (0.39) | TSHR | |
| SCHEMBL560824 | 0.75 | TDP1 (0.32) | — | |
| SCHEMBL8576781 | 0.75 | TSHR (0.50) | TSHR | |
| SCHEMBL16074682 | 0.73 | TSHR (0.48) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9187498-B2 | Compound and asymmetric synthesis reaction | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2015-11-17 | — | — | US | disclosed |
| US-20150183807-A1 | Compound and Asymmetric Synthesis Reaction | MICROBIAL CHEM RES FOUND (JP) | 2015-07-02 | — | — | US | disclosed |
| US-8981123-B2 | Compound and asymmetric synthesis reaction | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2015-03-17 | — | — | US | disclosed |
| US-20140296539-A1 | Compound and Asymmetric Synthesis Reaction | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2014-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150183807-A1 | Compound and Asymmetric Synthesis Reaction | CYP2E1, REV1, CYP19A1 | TSHR 2276/4885 |
| US-20140296539-A1 | Compound and Asymmetric Synthesis Reaction | CYP2E1, REV1, CYP19A1 | TSHR 2276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.