Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 20/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11903721 | 0.83 | CRHR1 (0.65) | CRHR1 | |
| SCHEMBL1613049 | 0.81 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL11920553 | 0.80 | CRHR1 (0.59) | CRHR1 | |
| SCHEMBL1614250 | 0.80 | CRHR1 (0.46) | CRHR1 | |
| SCHEMBL1614268 | 0.79 | CRHR1 (0.46) | CRHR1 | |
| SCHEMBL1613880 | 0.79 | CRHR1 (0.52) | CRHR1 | |
| SCHEMBL12712825 | 0.76 | CRHR1 (0.65) | CRHR1 | |
| SCHEMBL1613375 | 0.76 | CRHR1 (0.85) | CRHR1 | |
| SCHEMBL1613290 | 0.76 | CRHR1 (0.57) | CRHR1 | |
| SCHEMBL1660757 | 0.73 | CRHR1 (0.39) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8530504-B2 | Pyrazolothiazole compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2013-09-10 | — | — | US | disclosed |
| US-20110086882-A1 | PYRAZOLOTHIAZOLE COMPOUND | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086882-A1 | PYRAZOLOTHIAZOLE COMPOUND | CRHR1, CNR1, AGTR1 | CRHR1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.