Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 6/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15615899 | 0.91 | MTOR (0.46) | MTORCNR2MAPTMEN1KMT2A | |
| SCHEMBL18807465 | 0.74 | MTOR (0.52) | MTOR | |
| SCHEMBL15615969 | 0.71 | CNR2 (0.58) | CNR2SLC2A1BTK | |
| SCHEMBL17031570 | 0.70 | CNR2 (0.53) | CNR2MAPTMEN1KMT2ANPC1 | |
| SCHEMBL14978580 | 0.70 | DYRK1A (0.51) | MTORMAPTALDH1A1 | |
| SCHEMBL8324824 | 0.67 | GAA (0.50) | KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL8329323 | 0.66 | GAA (0.47) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL8328847 | 0.66 | PDE4B (0.56) | MAPTMEN1KMT2ASLC2A1ALDH1A1 | |
| SCHEMBL16086154 | 0.66 | MTOR (0.43) | MTOR | |
| Hydrochloric Acid SCHEMBL8330455 | 0.65 | MAPT (0.55) | MAPTMEN1KMT2ANPC1SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014154026-A1 | PI3K AND/OR mTOR INHIBITOR PRODRUG | 山东轩竹医药科技有限公司 (CN) | 2014-10-02 | — | — | WO | disclosed |