Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.49 |
| ▸ | BTK | Q06187 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | PDE2A | O00408 | 1/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | STAMBP | O95630 | 1/20 | 0.43 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15615969 | 0.89 | CNR2 (0.58) | CNR2SLC2A1BTKPOLB | |
| SCHEMBL15615899 | 0.80 | MTOR (0.46) | CNR2NPC1RAB9ASLC2A1BTK | |
| SCHEMBL17031567 | 0.80 | EGFR (0.49) | ALDH1A1KDM4ECSF1RMEN1KMT2A | |
| SCHEMBL17031568 | 0.79 | AURKB (0.57) | ALDH1A1KDM4EPKMMAPT | |
| SCHEMBL15615888 | 0.71 | LMNA (0.53) | ALDH1A1MAPTPOLB | |
| SCHEMBL16137602 | 0.70 | MTOR (0.45) | CNR2NPC1RAB9ASLC2A1BTK | |
| SCHEMBL5083313 | 0.69 | CNR2 (1.00) | CNR2 | |
| SCHEMBL12519685 | 0.69 | BTK (0.60) | CNR2NPC1RAB9ASLC2A1BTK | |
| SCHEMBL15615882 | 0.69 | MAPT (0.52) | ALDH1A1KDM4EPKMMAPT | |
| SCHEMBL5450303 | 0.69 | CNR2 (0.80) | CNR2NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9365572-B2 | PI3K and/or mTOR inhibitor | Xuanzhu Pharma Co., Ltd. (CN) | 2016-06-14 | — | — | US | disclosed |
| US-20150239885-A1 | PI3K AND/OR MTOR INHIBITOR | Xuanzhu Pharma Co., Ltd. (CN) | 2015-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150239885-A1 | PI3K AND/OR MTOR INHIBITOR | MTOR, RICTOR, RPTOR | CNR2 1868/4885NPC1 832/4885RAB9A 459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.