Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 6/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 6/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | VDR | P11473 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.31 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16139142 | 0.95 | CYP4F2 (0.36) | CYP4F2CYP4A11CNR1CNR2CYP1A2 | |
| SCHEMBL16138747 | 0.87 | ALDH1A1 (0.35) | CYP4F2CYP4A11CNR1CNR2ALDH1A1 | |
| SCHEMBL16138977 | 0.86 | CYP4F2 (0.39) | CYP4F2CYP4A11CNR1CNR2CYP1A2 | |
| SCHEMBL16138980 | 0.85 | CYP4F2 (0.38) | CYP4F2CYP4A11CNR1CNR2CYP1A2 | |
| SCHEMBL16138748 | 0.82 | CCR1 (0.39) | CYP4F2CYP4A11CNR1CNR2TSHR | |
| SCHEMBL16138826 | 0.81 | DGAT1 (0.32) | CNR1CNR2ALDH1A1KLF10 | |
| SCHEMBL16138827 | 0.80 | MEN1 (0.33) | ALDH1A1 | |
| SCHEMBL3006615 | 0.80 | CNR2 (0.41) | CNR2CYP2C19SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL31625015 | 0.80 | CNR2 (0.41) | CNR2CYP2C19SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL22119058 | 0.78 | PIN1 (0.45) | CYP4F2CYP4A11CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230255923-A1 | SHORT ACTING PHENYLALKYLAMINE CALCIUM CHANNEL BLOCKERS AND USES THEREOF | MILESTONE PHARMACEUTICALS INC (CA) | 2023-08-17 | — | — | US | disclosed |
| US-10010523-B2 | Short acting phenylalkylamine calcium channel blockers and uses thereof | MILESTONE PHARMACEUTICALS INC. (CA) | 2018-07-03 | — | — | US | disclosed |
| US-10010522-B2 | Short acting phenylalkylamine calcium channel blockers and uses thereof | MILESTONE PHARMACEUTICALS INC. (CA) | 2018-07-03 | — | — | US | disclosed |
| US-10010524-B2 | Short acting phenylalkylamine calcium channel blockers and uses thereof | MILESTONE PHARMACEUTICALS INC. (CA) | 2018-07-03 | — | — | US | disclosed |
| US-20170312243-A1 | SHORT ACTING PHENYLALKYLAMINE CALCIUM CHANNEL BLOCKERS AND USES THEREOF | ACQUIOM AGENCY SERVICES, LLC | 2017-11-02 | — | — | US | disclosed |
| US-20170312241-A1 | SHORT ACTING PHENYLALKYLAMINE CALCIUM CHANNEL BLOCKERS AND USES THEREOF | ACQUIOM AGENCY SERVICES, LLC | 2017-11-02 | — | — | US | disclosed |
| US-20170312242-A1 | SHORT ACTING PHENYLALKYLAMINE CALCIUM CHANNEL BLOCKERS AND USES THEREOF | ACQUIOM AGENCY SERVICES, LLC | 2017-11-02 | — | — | US | disclosed |
| US-9737503-B2 | Short acting phenylalkylamine calcium channel blockers and uses thereof | MILESTONE PHARMACEUTICALS INC. (CA) | 2017-08-22 | — | — | US | disclosed |
| US-20160374982-A1 | SHORT ACTING PHENYLALKYLAMINE CALCIUM CHANNEL BLOCKERS AND USES THEREOF | ACQUIOM AGENCY SERVICES, LLC | 2016-12-29 | — | — | US | disclosed |
| US-9463179-B2 | Short acting phenylalkylamine calcium channel blockers and uses thereof | MILESTONE PHARMACEUTICALS INC. (CA) | 2016-10-11 | — | — | US | disclosed |
| US-20160074354-A1 | SHORT ACTING PHENYLALKYLAMINE CALCIUM CHANNEL BLOCKERS AND USES THEREOF | ACQUIOM AGENCY SERVICES, LLC | 2016-03-17 | — | — | US | disclosed |
| US-9227918-B2 | Short acting phenylalkylamine calcium channel blockers and uses thereof | MILESTONE PHARMACEUTICALS (CA) | 2016-01-05 | — | — | US | disclosed |
| US-20140296335-A1 | SHORT ACTING PHENYLALKYLAMINE CALCIUM CHANNEL BLOCKERS AND USES THEREOF | ACQUIOM AGENCY SERVICES, LLC | 2014-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230255923-A1 | SHORT ACTING PHENYLALKYLAMINE CALCIUM CHANNEL BLOCKERS AND USES THEREOF | ORAI1, ATP2A1, RYR2 | CYP4F2 3383/4885CYP4A11 2712/4885CNR1 770/4885 |
| US-20160374982-A1 | SHORT ACTING PHENYLALKYLAMINE CALCIUM CHANNEL BLOCKERS AND USES THEREOF | ORAI1, ATP2A1, RYR2 | CYP4F2 3383/4885CYP4A11 2712/4885CNR1 770/4885 |
| US-20170312243-A1 | SHORT ACTING PHENYLALKYLAMINE CALCIUM CHANNEL BLOCKERS AND USES THEREOF | ORAI1, ATP2A1, RYR2 | CYP4F2 3383/4885CYP4A11 2712/4885CNR1 770/4885 |
| US-10010524-B2 | Short acting phenylalkylamine calcium channel blockers and uses thereof | ORAI1, ATP2A1, RYR2 | CYP4F2 3383/4885CYP4A11 2712/4885CNR1 770/4885 |
| US-20140296335-A1 | SHORT ACTING PHENYLALKYLAMINE CALCIUM CHANNEL BLOCKERS AND USES THEREOF | ORAI1, ATP2A1, RYR2 | CYP4F2 3383/4885CYP4A11 2712/4885CNR1 770/4885 |
| US-10010522-B2 | Short acting phenylalkylamine calcium channel blockers and uses thereof | ORAI1, ATP2A1, RYR2 | CYP4F2 3383/4885CYP4A11 2712/4885CNR1 770/4885 |
| US-20160074354-A1 | SHORT ACTING PHENYLALKYLAMINE CALCIUM CHANNEL BLOCKERS AND USES THEREOF | ORAI1, ATP2A1, RYR2 | CYP4F2 3383/4885CYP4A11 2712/4885CNR1 770/4885 |
| US-20170312241-A1 | SHORT ACTING PHENYLALKYLAMINE CALCIUM CHANNEL BLOCKERS AND USES THEREOF | ORAI1, ATP2A1, RYR2 | CYP4F2 3383/4885CYP4A11 2712/4885CNR1 770/4885 |
| US-10010523-B2 | Short acting phenylalkylamine calcium channel blockers and uses thereof | ORAI1, ATP2A1, RYR2 | CYP4F2 3383/4885CYP4A11 2712/4885CNR1 770/4885 |
| US-20170312242-A1 | SHORT ACTING PHENYLALKYLAMINE CALCIUM CHANNEL BLOCKERS AND USES THEREOF | ORAI1, ATP2A1, RYR2 | CYP4F2 3383/4885CYP4A11 2712/4885CNR1 770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.