Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.31 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.31 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6617335 | 0.85 | OPRL1 (0.41) | OPRL1SLC6A2SLC6A4SLC6A3OPRM1 | |
| SCHEMBL7498360 | 0.85 | CYP11B1 (0.36) | OPRL1SLC6A2SLC6A4SLC6A3CHRNB2 | |
| SCHEMBL7223397 | 0.85 | OPRL1 (0.36) | OPRL1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7228554 | 0.85 | CHRNB2 (0.43) | OPRL1SLC6A2SLC6A4SLC6A3OPRM1 | |
| SCHEMBL7223956 | 0.85 | OPRL1 (0.36) | OPRL1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7223737 | 0.85 | OPRL1 (0.36) | OPRL1SLC6A2SLC6A4SLC6A3OPRM1 | |
| SCHEMBL7222900 | 0.85 | OPRL1 (0.36) | OPRL1SLC6A2SLC6A4SLC6A3RIPK2 | |
| SCHEMBL7230387 | 0.83 | KMT2A (0.40) | OPRL1CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL7229415 | 0.83 | CHRNA3 (0.40) | OPRL1SLC6A2SLC6A4SLC6A3CHRNB2 | |
| SCHEMBL16139989 | 0.83 | CHRNA3 (0.40) | OPRL1SLC6A2SLC6A4SLC6A3CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014154486-A1 | METHODS OF CONTROLLING NEONICOTINOID RESISTANT PESTS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-02 | — | — | WO | disclosed |