Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.42 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PYGL | P06737 | 1/20 | 0.32 |
| ▸ | TGM2 | P21980 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL106883 | 0.88 | TSHR (0.54) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 | |
| SCHEMBL31224580 | 0.86 | TSHR (0.52) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 | |
| Acrylamide SCHEMBL20553509 | 0.81 | TSHR (0.46) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 | |
| SCHEMBL2132212 | 0.79 | TSHR (0.45) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 | |
| SCHEMBL21506692 | 0.79 | TSHR (0.52) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 | |
| SCHEMBL21318126 | 0.78 | ZDHHC20 (0.46) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 | |
| SCHEMBL22861299 | 0.76 | ALDH1A1 (0.54) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 | |
| SCHEMBL18884533 | 0.75 | ALDH1A1 (0.41) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 | |
| SCHEMBL24628353 | 0.73 | ALDH1A1 (0.38) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 | |
| SCHEMBL21318152 | 0.73 | ZDHHC20 (0.41) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9802984-B2 | Biomimetic peptide and biodegradable delivery platform for the treatment of angiogenesis- and lymphangiogenesis-dependent diseases | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-10-31 | — | — | US | disclosed |
| US-9717694-B2 | Peptide/particle delivery systems | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-08-01 | — | — | US | disclosed |
| US-20170143639-A1 | NANOCOMPOSITES OF GOLD AND POLYMERS | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-05-25 | — | — | US | disclosed |
| US-20160122390-A1 | A BIOMIMETIC PEPTIDE AND BIODEGRADABLE DELIVERY PLATFORM FOR THE TREATMENT OF ANGIOGENESIS- AND LYMPHANGIOGENESIS-DEPENDENT DISEASES | THE JOHNS HOPKINS UNIVERSITY (US) | 2016-05-05 | — | — | US | disclosed |
| US-20140294909-A1 | NANOCOMPOSITES OF GOLD AND POLYMERS | THE JOHNS HOPKINS UNIVERSITY (US) | 2014-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160122390-A1 | A BIOMIMETIC PEPTIDE AND BIODEGRADABLE DELIVERY PLATFORM FOR THE TREATMENT OF ANGIOGENESIS- AND LYMPHANGIOGENESIS-DEPENDENT DISEASES | VEGFA, LRRFIP1, FLT1 | ALDH1A1 3688/4885TSHR 2524/4885MAPK1 1822/4885 |
| US-20170143639-A1 | NANOCOMPOSITES OF GOLD AND POLYMERS | HNRNPL, HNRNPLL, ACSL3 | ALDH1A1 883/4885TSHR 1764/4885MAPK1 3583/4885 |
| US-20140294909-A1 | NANOCOMPOSITES OF GOLD AND POLYMERS | HNRNPL, HNRNPLL, ACSL3 | ALDH1A1 883/4885TSHR 1764/4885MAPK1 3583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.