Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | STAT1 | P42224 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16143885 | 0.93 | MAPT (0.34) | F2RMAPTHPGDALDH1A1KDM4E | |
| SCHEMBL125755 | 0.87 | ALDH1A1 (0.39) | MAPTHPGDALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL16143796 | 0.80 | PTPN1 (0.36) | MAPTHPGDALDH1A1KDM4ENPSR1 | |
| SCHEMBL123522 | 0.80 | ADRB2 (0.42) | MAPTHPGDALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL12018021 | 0.79 | ALDH1A1 (0.47) | F2RMAPTHPGDALDH1A1KDM4E | |
| SCHEMBL12019253 | 0.78 | TSHR (0.40) | MAPTHPGDALDH1A1KDM4ENPC1 | |
| SCHEMBL12018017 | 0.77 | F2R (0.45) | F2RMAPTHPGDALDH1A1KDM4E | |
| SCHEMBL12018022 | 0.72 | ALDH1A1 (0.45) | MAPTHPGDALDH1A1KDM4ENPC1 | |
| SCHEMBL9615565 | 0.71 | ALDH1A1 (0.45) | HPGDALDH1A1KDM4ETDP1TP53 | |
| SCHEMBL12018026 | 0.71 | ALDH1A1 (0.51) | HPGDALDH1A1KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2496549-B1 | NEW, NON-CRYSTALLISING METHACRYLATE, ITS MANUFACTURE AND APPLICATION | BAYER IP GMBH (DE) | 2014-10-08 | — | — | EP | disclosed |