Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | CASP1 | P29466 | 5/20 | 0.74 |
| ▸ | CASP7 | P55210 | 5/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.74 |
| ▸ | MEN1 | O00255 | 4/20 | 0.74 |
| ▸ | LMNA | P02545 | 3/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.74 |
| ▸ | NPC1 | O15118 | 4/20 | 0.71 |
| ▸ | HPGD | P15428 | 3/20 | 0.71 |
| ▸ | TSHR | P16473 | 8/20 | 0.65 |
| ▸ | USP2 | O75604 | 4/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.65 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 4/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10770348 | 0.98 | ALDH1A1 (0.97) | ALDH1A1CASP1CASP7KMT2AHSD17B10 | |
| SCHEMBL9436911 | 0.87 | ALDH1A1 (0.77) | ALDH1A1CASP1CASP7KMT2AHSD17B10 | |
| SCHEMBL9436888 | 0.83 | ALDH1A1 (0.71) | ALDH1A1CASP1CASP7KMT2AHSD17B10 | |
| SCHEMBL18249665 | 0.81 | CTNNB1 (0.77) | ALDH1A1CASP1CASP7KMT2AHSD17B10 | |
| SCHEMBL5524713 | 0.79 | MAPT (1.00) | ALDH1A1CASP1CASP7KMT2AHSD17B10 | |
| SCHEMBL9706282 | 0.76 | TSHR (0.72) | ALDH1A1CASP1CASP7KMT2AHSD17B10 | |
| SCHEMBL15289657 | 0.76 | TSHR (0.72) | ALDH1A1CASP1CASP7KMT2AHSD17B10 | |
| SCHEMBL5530202 | 0.76 | TSHR (1.00) | ALDH1A1CASP1CASP7KMT2AHSD17B10 | |
| SCHEMBL8758392 | 0.75 | ALDH1A1 (0.59) | ALDH1A1CASP1CASP7KMT2AHSD17B10 | |
| SCHEMBL5522487 | 0.75 | TSHR (0.69) | ALDH1A1CASP1CASP7KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756111-B1 | ALKYL SUBSTITUTED INDOLOQUINOXALINES | OXYPHARMA AB (SE) | 2010-03-31 | — | — | EP | claimed |
| US-20100009999-A1 | ALKYL SUBSTITUTED INDOLOQUINOXALINES | OXYPHARMA AB (SE) | 2010-01-14 | — | — | US | claimed |
| JP-2008502676-A | — | — | 2008-01-31 | — | — | JP | claimed |
| EP-1756111-A1 | ALKYL SUBSTITUTED INDOLOQUINOXALINES | Oxypharma AB (SE) | 2007-02-28 | — | — | EP | claimed |
| US-20050288296-A1 | Alkyl substituted indoloquinoxalines | CYXONE AB, 559020-5471 (SE) | 2005-12-29 | — | — | US | claimed |
| WO-2005123741-A1 | ALKYL SUBSTITUTED INDOLOQUINOXALINES | OXYPHARMA AB (SE) | 2005-12-29 | — | — | WO | claimed |
| US-8084453-B2 | Alkyl substituted indoloquinoxalines | OXYPHARMA AB (SE) | 2011-12-27 | — | — | US | disclosed |
| US-20110086859-A9 | ALKYL SUBSTITUTED INDOLOQUINOXALINES | OXYPHARMA AB (SE) | 2011-04-14 | — | — | US | disclosed |
| EP-1756111-B1 | ALKYL SUBSTITUTED INDOLOQUINOXALINES | OXYPHARMA AB (SE) | 2010-03-31 | — | — | EP | disclosed |
| US-20100009999-A1 | ALKYL SUBSTITUTED INDOLOQUINOXALINES | OXYPHARMA AB (SE) | 2010-01-14 | — | — | US | disclosed |
| US-7589093-B2 | 2,3-Dimethylindolo[2,3-b]quinoxaline-6-yl-acetamide; 9-Chloro-2,3-dimethyl-6-(aminoethylamino-2-oxoethyl)-6H-indolo[2,3-b]quinoxaline; autoimmune diseases | OXYPHARMA AB (SE) | 2009-09-15 | — | — | US | disclosed |
| EP-1756111-A1 | ALKYL SUBSTITUTED INDOLOQUINOXALINES | Oxypharma AB (SE) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005123741-A1 | ALKYL SUBSTITUTED INDOLOQUINOXALINES | OXYPHARMA AB (SE) | 2005-12-29 | — | — | WO | disclosed |
| EP-0238459-B1 | SUBSTITUTED INDOLOQUINOXALINES | Lundblad, Leif (SE) | 1992-04-15 | — | — | EP | disclosed |
| US-4990510-A | Viricides, anticancer agents | LEIF LUNDBLAD (BE) | 1991-02-05 | — | — | US | disclosed |
| US-4916124-A | Indoloquinoxalines with substituents in 6-position containing cyclic groups as antiviral agents | Lundblad, Lief (SE) | 1990-04-10 | — | — | US | disclosed |
| EP-0238459-A1 | Substituted indoloquinoxalines | Lundblad, Leif (SE) | 1987-09-23 | — | — | EP | disclosed |
| EP-0231159-A1 | Indoloquinoxalines with substituents in 6-position containing cyclic groups | Lundblad, Leif (SE) | 1987-08-05 | — | — | EP | disclosed |
| WO-1987004436-A1 | SUBSTITUTED INDOLOQUINOXALINES | LUNDBLAD, LEIF (SE) | 1987-07-30 | — | — | WO | disclosed |
| WO-1987004437-A1 | INDOLOQUINOXALINES WITH SUBSTITUENTS IN 6-POSITION CONTAINING CYCLIC GROUPS | LUNDBLAD, LEIF (SE) | 1987-07-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086859-A9 | ALKYL SUBSTITUTED INDOLOQUINOXALINES | HRH4, HRH3, NR4A1 | ALDH1A1 3537/4885CASP1 2802/4885CASP7 2201/4885 |
| US-20100009999-A1 | ALKYL SUBSTITUTED INDOLOQUINOXALINES | HRH4, HRH3, NR4A1 | ALDH1A1 3537/4885CASP1 2802/4885CASP7 2201/4885 |
| US-20050288296-A1 | Alkyl substituted indoloquinoxalines | HRH4, HRH3, NR4A1 | ALDH1A1 3537/4885CASP1 2802/4885CASP7 2201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.