SCHEMBL16144404

SCHEMBL16144404

Fc1ccccc1N(c1ccccc1)c1ccc2ccc3c(N(c4ccc5ccccc5c4)c4ncccn4)ccc4ccc1c2c43

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
TSHR P16473 1/20 0.32
HTT P42858 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16144382 0.92 ALDH1A1 (0.31) ALDH1A1
SCHEMBL16144483 0.90 ALDH1A1 (0.31) ALDH1A1LMNATSHRHTTNPSR1
SCHEMBL16144403 0.90
SCHEMBL16144405 0.87 SYK (0.31)
SCHEMBL16144429 0.86
SCHEMBL16144407 0.86 NPC1 (0.33)
SCHEMBL16144408 0.86 CCR1 (0.31) LMNATSHRHTTL3MBTL1
SCHEMBL16144393 0.85 SLC6A2 (0.31)
SCHEMBL16144456 0.85 NOS3 (0.32)
SCHEMBL16144506 0.84 NCF1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9583718-B2 Pyrene-based compound and organic light-emitting diode including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-02-28 US disclosed
US-9583718-B2 Pyrene-based compound and organic light-emitting diode including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-02-28 US disclosed
US-20140291646-A1 PYRENE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-10-02 US disclosed
US-20140291646-A1 PYRENE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-10-02 US disclosed