SCHEMBL16144605

SCHEMBL16144605

COP(C)(=O)OP(=O)(O)O

nearest known ligand 0.50

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.50
BLM P54132 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
CA2 P00918 1/20 0.39
BTN3A1 O00481 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16144604 0.87 FDPS (0.43) FDPSBLMTDP1CA2BTN3A1
SCHEMBL338802 0.84 FDPS (0.60) FDPSBLMTDP1CA2BTN3A1
SCHEMBL12736932 0.82 CA2 (0.39) FDPSBLMTDP1CA2
SCHEMBL15437535 0.81 ALDH1A1 (0.32) CA2
SCHEMBL24469373 0.80 CA2 (0.37) FDPSBLMTDP1CA2BTN3A1
Dimethyl Methylphosphonate SCHEMBL29023322 0.78 CA2 (0.57) FDPSBLMTDP1CA2
Dimethyl Methylphosphonate SCHEMBL7159496 0.78 CA2 (0.47) FDPSBLMTDP1CA2
Dimethyl Methylphosphonate SCHEMBL7162647 0.78 CA2 (0.47) FDPSBLMTDP1CA2
Phosphoric Acid Monomethyl Ester SCHEMBL30118383 0.77
Dimethyl Methylphosphonate SCHEMBL30950306 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9187515-B2 2′,4′-fluoro nucleosides for the treatment of HCV IDENIX PHARMACEUTICALS LLC (US) 2015-11-17 US disclosed
US-20140294769-A1 2',4'-FLUORO NUCLEOSIDES FOR THE TREATMENT OF HCV IDENIX PHARMACEUTICALS LLC 2014-10-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140294769-A1 2',4'-FLUORO NUCLEOSIDES FOR THE TREATMENT OF HCV SLC29A1, SLC28A1, SLC10A1 FDPS 618/4885BLM 1558/4885TDP1 180/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.