SCHEMBL1614519

SCHEMBL1614519

CCCC(CO)C(CO)CC(C)C

nearest known ligand 0.46

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.46
LMNA P02545 2/20 0.44
METAP1 P53582 1/20 0.32
ALDH1A1 P00352 1/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1613897 0.86 ALDH1A1 (0.43) TSHRLMNAALDH1A1
SCHEMBL1614926 0.84 LMNA (0.57) TSHRLMNAMETAP1ALDH1A1TDP1
SCHEMBL3671978 0.81 LMNA (0.52) TSHRLMNAMETAP1TDP1
SCHEMBL17464910 0.81 LMNA (0.64) TSHRLMNATDP1
SCHEMBL3082026 0.81 LMNA (0.55) TSHRLMNAMETAP1ALDH1A1TDP1
SCHEMBL13143420 0.81 TSHR (0.50) TSHRLMNAALDH1A1TDP1
SCHEMBL1614311 0.79 LMNA (0.42) TSHRLMNAALDH1A1TDP1
SCHEMBL17464917 0.79 LMNA (0.42) TSHRLMNAALDH1A1TDP1
SCHEMBL14284905 0.76
SCHEMBL7391772 0.76 TSHR (0.33) TSHRMETAP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110086975-A1 COLORED GEL COAT COMPOSITION AND ARTICLE VALSPAR SOURCING, INC. 2011-04-14 US disclosed