Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | CA1 | P00915 | 3/20 | 0.60 |
| ▸ | CA2 | P00918 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | CA12 | O43570 | 2/20 | 0.60 |
| ▸ | CA7 | P43166 | 2/20 | 0.60 |
| ▸ | CA9 | Q16790 | 2/20 | 0.60 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.60 |
| ▸ | CA4 | P22748 | 1/20 | 0.60 |
| ▸ | CA6 | P23280 | 1/20 | 0.60 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.60 |
| ▸ | G6PD | P11413 | 1/20 | 0.57 |
| ▸ | CASP7 | P55210 | 1/20 | 0.57 |
| ▸ | CASP6 | P55212 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8797994 | 0.98 | TSHR (0.63) | TSHRALDH1A1KDM4ECA1CA2 | |
| SCHEMBL1614730 | 0.85 | TSHR (0.77) | TSHRALDH1A1KDM4ECA1CA2 | |
| Hydrochloric Acid SCHEMBL11483376 | 0.83 | TSHR (0.74) | TSHRALDH1A1KDM4ECA1CA2 | |
| Hydrochloric Acid SCHEMBL21808814 | 0.83 | TSHR (0.74) | TSHRALDH1A1KDM4ECA1CA2 | |
| SCHEMBL29386013 | 0.82 | ALDH1A1 (0.55) | TSHRALDH1A1KDM4ECA1CA2 | |
| SCHEMBL23413049 | 0.80 | KDM4E (0.61) | TSHRALDH1A1KDM4ECA1CA2 | |
| SCHEMBL3254784 | 0.80 | THRB (0.52) | TSHRALDH1A1KDM4ECA1CA2 | |
| SCHEMBL29779531 | 0.80 | THRB (0.52) | TSHRALDH1A1KDM4ECA1CA2 | |
| SCHEMBL9393687 | 0.79 | ALDH1A1 (0.54) | TSHRALDH1A1KDM4ECA1CA2 | |
| SCHEMBL19923193 | 0.79 | TSHR (0.68) | TSHRALDH1A1KDM4ECA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130184429-A1 | FUNCTIONAL BIODEGRADABLE POLYMERS | THE UNIVERSITY OF AKRON (US) | 2013-07-18 | — | — | US | claimed |
| EP-2598552-A1 | FUNCTIONAL BIODEGRADABLE POLYMERS | University Of Akron (US) | 2013-06-05 | — | — | EP | claimed |
| WO-2012015481-A1 | FUNCTIONAL BIODEGRADABLE POLYMERS | UNIVERSITY OF AKRON (US) | 2012-02-02 | — | — | WO | claimed |
| US-20090130739-A1 | Deactivation of mineral encapsulated nanobacteria | AMERICAN STERILIZER COMPANY (US) | 2009-05-21 | — | — | US | claimed |
| CN-1009086-B | Process for preparing tri-substituted benzoic acid intermediates | STAUFFER CHEMICAL CO (US) | 1990-08-08 | — | — | CN | claimed |
| CN-86101277-A | Trisubstituted phenylformic acid intermediates preparation | — | 1986-11-19 | — | — | CN | claimed |
| US-12577243-B2 | Monoacylglycerol lipase modulators | JANSSEN PHARMACEUTICA NV (BE) | 2026-03-17 | — | — | US | disclosed |
| EP-3856178-B1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2026-03-11 | — | — | EP | disclosed |
| US-20240360085-A1 | Glucose Uptake Inhibitors | KADMON CORPORATION, LLC (US) | 2024-10-31 | — | — | US | disclosed |
| CN-113164459-B | Monoacylglycerol lipase modulators | 詹森药业有限公司 | 2024-09-03 | — | — | CN | disclosed |
| US-12030857-B2 | Glucose uptake inhibitors | KADMON CORPORATION, LLC (US) | 2024-07-09 | — | — | US | disclosed |
| US-12005089-B2 | CVS transplantation for treatment of bacterial vaginosis | THE JOHNS HOPKINS UNIVERSITY (US) | 2024-06-11 | — | — | US | disclosed |
| US-11820766-B2 | Monoacylglycerol lipase modulators | JANSSEN PHARMACEUTICA NV (BE) | 2023-11-21 | — | — | US | disclosed |
| EP-0276729-A2 | Process for the decomposition of aromatic compounds by Rhodococcus rhodochrous | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-03 | — | — | EP | disclosed |
| EP-0222608-A2 | Derivatives of p-guanidinobenzoic acid and pharmaceutical agents containing them as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 1987-05-20 | — | — | EP | disclosed |
| EP-0206543-A2 | Polyaromatic compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-12-30 | — | — | EP | disclosed |
| CN-86101277-A | Trisubstituted phenylformic acid intermediates preparation | — | 1986-11-19 | — | — | CN | disclosed |
| EP-0044205-B1 | POLYESTER OF 6-HYDROXY-2-NAPHTHOIC ACID AND METAHYDROXY BENZOIC ACID CAPABLE OF READILY UNDERGOING MELT PROCESSING | CELANESE CORPORATION (US) | 1985-04-10 | — | — | EP | disclosed |
| US-4337190-A | Polyester of 6-hydroxy-2-naphthoic acid and meta-hydroxy benzoic acid capable of readily undergoing melt processing | CELANESE CORPORATION (US) | 1982-06-29 | — | — | US | disclosed |
| EP-0044205-A1 | Polyester of 6-hydroxy-2-naphthoic acid and metahydroxy benzoic acid capable of readily undergoing melt processing | CELANESE CORPORATION (US) | 1982-01-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12030857-B2 | Glucose uptake inhibitors | SLC2A1, SLC2A4, SLC2A2 | TSHR 3168/4885ALDH1A1 1422/4885KDM4E 2325/4885 |
| US-12577243-B2 | Monoacylglycerol lipase modulators | MGLL, LPL, FAAH | TSHR 400/4885ALDH1A1 587/4885KDM4E 3565/4885 |
| US-20240360085-A1 | Glucose Uptake Inhibitors | SLC2A3, SLC2A1, SLC2A4 | TSHR 2854/4885ALDH1A1 1565/4885KDM4E 2173/4885 |
| US-11820766-B2 | Monoacylglycerol lipase modulators | MGLL, LPL, PNLIP | TSHR 909/4885ALDH1A1 312/4885KDM4E 2437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.