SCHEMBL1614745

SCHEMBL1614745

O=C(O)C(=CC=Cc1ccccc1)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.54
LMNA P02545 6/20 0.52
ALDH1A1 P00352 3/20 0.52
TRPA1 O75762 1/20 0.52
ALOX5 P09917 1/20 0.52
MAPK1 P28482 1/20 0.52
MCL1 Q07820 1/20 0.51
GRIK1 P39086 1/20 0.51
HDAC3 O15379 3/20 0.50
HDAC4 P56524 3/20 0.50
HDAC1 Q13547 3/20 0.50
HDAC2 Q92769 3/20 0.50
HDAC8 Q9BY41 3/20 0.50
HDAC6 Q9UBN7 3/20 0.50
MAPT P10636 3/20 0.50
HDAC7 Q8WUI4 2/20 0.50
HDAC10 Q969S8 2/20 0.50
HDAC11 Q96DB2 2/20 0.50
HDAC9 Q9UKV0 2/20 0.50
HDAC5 Q9UQL6 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1614744 1.00 MAOB (0.54) MAOBLMNAALDH1A1TRPA1ALOX5
SCHEMBL11038794 0.88 GLA (0.50) MAOBLMNAALDH1A1TRPA1ALOX5
SCHEMBL11038792 0.88 GLA (0.50) MAOBLMNAALDH1A1TRPA1ALOX5
SCHEMBL11050801 0.85 GRIK1 (0.44) MAOBLMNAALDH1A1TRPA1ALOX5
SCHEMBL11050802 0.85 GRIK1 (0.44) MAOBLMNAALDH1A1TRPA1ALOX5
SCHEMBL8862864 0.85 GRIK1 (0.44) MAOBLMNAALDH1A1TRPA1ALOX5
SCHEMBL10620497 0.84 LMNA (0.60) LMNAALDH1A1HDAC3HDAC4HDAC1
SCHEMBL12294102 0.84 APP (0.42) MAOBLMNAALDH1A1MCL1GRIK1
SCHEMBL10944462 0.83 GLA (0.53) MAOBLMNAALDH1A1TRPA1ALOX5
SCHEMBL4452595 0.83 MAOB (0.50) MAOBLMNAALDH1A1TRPA1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5981651-A Ink processes XEROX CORPORATION (US) 1999-11-09 US claimed
US-5376503-A A photo-crosslinkable blends consisting of an isoolefin, a para-alkylstyrene and a photoinitiator substituted on the alkyl group of para-alkylstyrene monomers; corrosion, solvent resistance EXXON CHEMICAL PATENTS INC. (US) 1994-12-27 US claimed
EP-0563251-A1 UV/EB CURABLE BUTYL COPOLYMERS FOR LITHOGRAPHIC AND CORROSION-RESISTANT COATING APPLICATIONS EXXON CHEMICAL PATENTS INC. (US) 1993-10-06 EP claimed
EP-0563271-A1 UV/EB CURABLE BUTYL COPOLYMERS FOR COATING APPLICATIONS EXXON CHEMICAL PATENTS INC. (US) 1993-10-06 EP claimed
WO-1992011322-A2 UV/EB CURABLE BUTYL COPOLYMERS FOR LITHOGRAPHIC AND CORROSION-RESISTANT COATING APPLICATIONS EXXON CHEMICAL PATENTS INC. (US) 1992-07-09 WO claimed
WO-1992011295-A1 UV/EB CURABLE BUTYL COPOLYMERS FOR COATING APPLICATIONS EXXON CHEMICAL PATENTS INC. (US) 1992-07-09 WO claimed
US-4743527-A LITHOGRAPHY FUJI PHOTO FILM CO., LTD. (JP) 1988-05-10 US claimed
EP-0165710-A1 Benzene sulfonate quaternary ammonium salts of organic sunscreen carboxylic acids VAN DYK & COMPANY, INC. (US) 1985-12-27 EP claimed
EP-0035886-B1 SOLID-STATE IMAGING DEVICE HAVING A COLOR FILTER ARRAY AND METHODS OF PREPARING SAME EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1985-11-27 EP claimed
US-4315978-A Solid-state color imaging device having a color filter array using a photocrosslinkable barrier EASTMAN KODAK COMPANY (US) 1982-02-16 US claimed
EP-0035886-A2 Solid-state imaging device having a color filter array and methods of preparing same EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1981-09-16 EP claimed
US-4101326-A Process for making stabilized polyesters used in radiation-sensitive compositions for lithographic plates having improved wear life including hindered phenols and phosphoric acid esters EASTMAN KODAK COMPANY (US) 1978-07-18 US claimed
JP-10279477-A None JP disclosed
JP-7017912-A None JP disclosed
US-20240066001-A1 METHODS AND COMPOSITIONS FOR TREATING OBESITY, PREVENTING WEIGHT GAIN, PROMOTING WEIGHT LOSS, PROMOTING SLIMMING, OR TREATING OR PREVENTING THE DEVELOPMENT OF DIABETES SILTI AG (CH) 2024-02-29 US disclosed
EP-3164125-B1 METHODS AND COMPOSITIONS FOR TREATING OBESITY, PREVENTING WEIGHT GAIN, PROMOTING WEIGHT LOSS, PROMOTING SLIMMING, OR TREATING OR PREVENTING THE DEVELOPMENT OF DIABETES NAN GLOBAL LLC (US) 2023-09-06 EP disclosed
US-4097282-A SILVER HALIDE, POLYESTER ADHESIVE EASTMAN KODAK COMPANY (US) 1978-06-27 US disclosed
US-4078229-A Three dimensional systems SWANSON WYN K 1978-03-07 US disclosed
US-4020230-A Microporous polyethylene hollow fibers and process of preparing them THE DOW CHEMICAL COMPANY (US) 1977-04-26 US disclosed
US-3938992-A Electrographic developing composition and process using a fusible, crosslinked binder polymer EASTMAN KODAK COMPANY (US) 1976-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240066001-A1 METHODS AND COMPOSITIONS FOR TREATING OBESITY, PREVENTING WEIGHT GAIN, PROMOTING WEIGHT LOSS, PROMOTING SLIMMING, OR TREATING OR PREVENTING THE DEVELOPMENT OF DIABETES GPR119, CPT1B, CPT2 MAOB 2481/4885LMNA 521/4885ALDH1A1 3375/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.