SCHEMBL1614770

SCHEMBL1614770

Cc1cc(N(C)C)ccc1/N=N/c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.61
ALDH1A1 P00352 4/20 0.61
MAPK1 P28482 3/20 0.61
TSHR P16473 2/20 0.61
HSD17B10 Q99714 1/20 0.61
NPC1 O15118 5/20 0.58
KMT2A Q03164 5/20 0.58
RAB9A P51151 4/20 0.58
MEN1 O00255 4/20 0.58
L3MBTL1 Q9Y468 2/20 0.58
MAPT P10636 1/20 0.58
ATM Q13315 1/20 0.58
CASP3 P42574 2/20 0.51
SENP8 Q96LD8 2/20 0.51
SENP7 Q9BQF6 2/20 0.51
SENP6 Q9GZR1 2/20 0.51
NSD2 O96028 1/20 0.51
ALPL P05186 1/20 0.50
ALPI P09923 1/20 0.50
ALPG P10696 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1614771 1.00 TDP1 (0.61) TDP1ALDH1A1MAPK1TSHRHSD17B10
SCHEMBL30569593 1.00 TDP1 (0.61) TDP1ALDH1A1MAPK1TSHRHSD17B10
SCHEMBL12471025 0.98 TDP1 (0.65) TDP1ALDH1A1MAPK1TSHRHSD17B10
SCHEMBL11508824 0.91 NPC1 (0.62) TDP1ALDH1A1MAPK1TSHRHSD17B10
SCHEMBL11036686 0.90 MAPK1 (0.68) TDP1ALDH1A1MAPK1TSHRHSD17B10
SCHEMBL28862112 0.85 TDP1 (0.59) TDP1ALDH1A1MAPK1TSHRHSD17B10
SCHEMBL14366699 0.83 NPC1 (0.59) TDP1ALDH1A1MAPK1TSHRHSD17B10
SCHEMBL8854399 0.83 TDP1 (0.61) TDP1ALDH1A1MAPK1TSHRHSD17B10
SCHEMBL8854396 0.83 TDP1 (0.61) TDP1ALDH1A1MAPK1TSHRHSD17B10
SCHEMBL11048726 0.82 NPC1 (0.59) TDP1ALDH1A1MAPK1TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122070479-A Ultrasonic indicating device and method for monitoring ultrasonic treatment JP实验室股份有限公司 2026-05-19 CN claimed
WO-2025090061-A1 ULTRASONIC INDICATOR DEVICE AND METHOD FOR MONITORING ULTRASONICATION JP LABORATORIES, INC. (US) 2025-05-01 WO claimed
US-20240383170-A1 FLEXIBLE AND SMART WOOD WITH RESPONSIVE FUNCTION, PREPARATION METHOD THEREOF AND ACTUATOR NANJING FORESTRY UNIVERSITY (CN) 2024-11-21 US claimed
WO-2024234393-A1 FLEXIBLE INTELLIGENT WOOD HAVING RESPONSE FUNCTION, ACTUATOR, AND MANUFACTURING METHOD 南京林业大学 2024-11-21 WO claimed
CN-116373056-B Flexible intelligent wood with responsiveness function, actuator and preparation method 南京林业大学 2023-12-12 CN claimed
CN-116373056-A Flexible intelligent wood with responsiveness function, actuator and preparation method 南京林业大学 2023-07-04 CN claimed
US-7611545-B2 Cosmetic article and process for dry dyeing keratin materials L'OREAL S.A. (FR) 2009-11-03 US claimed
US-20080244837-A1 Cosmetic article and process for dry dyeing keratin materials L'OREAL S.A. (FR) 2008-10-09 US claimed
EP-1964539-A1 Cosmetic article for dyeing dry hair, its use, method of implementing said article L'Oréal (FR) 2008-09-03 EP claimed
US-20080148496-A1 Dyeing of in Particular Human Keratin Materials by Dry Thermal Transfer of a Direct Dye, Composition Comprising the Said Dye and Its Method of Preparation L'OREAL S.A. (FR) 2008-06-26 US claimed
EP-1855643-A1 DYEING OF IN PARTICULAR HUMAN KERATIN MATERIALS BY DRY THERMAL TRANSFER OF A DIRECT DYE, COMPOSITION COMPRISING THE SAID DYE AND ITS METHOD OF PREPARATION L'OREAL (FR) 2007-11-21 EP claimed
WO-2006089806-A1 DYEING OF IN PARTICULAR HUMAN KERATIN MATERIALS BY DRY THERMAL TRANSFER OF A DIRECT DYE, COMPOSITION COMPRISING THE SAID DYE AND ITS METHOD OF PREPARATION L'ORÉAL (FR) 2006-08-31 WO claimed
WO-2006060654-A2 PESTICIDAL COMPOSITIONS AND METHODS DIVERGENCE, INC. (US) 2006-06-08 WO claimed
US-20050203067-A1 Pesticidal compositions and methods DIVERGENCE, INC. 2005-09-15 US claimed
US-6531581-B1 When incorporated into hairpin oligonucleotides these quench the fluorescence of fluorophores linked to the 5'-terminus of the oligonucleotide SEROLOGICALS, INC. 2003-03-11 US claimed
EP-1086115-A2 PURINES AND PYRIMIDINES LINKED TO A QUENCHER Intergen Company (US) 2001-03-28 EP claimed
WO-1999064431-A2 PURINES AND PYRIMIDINES LINKED TO A QUENCHER INTERGEN COMPANY (US) 1999-12-16 WO claimed
CN-122070479-A Ultrasonic indicating device and method for monitoring ultrasonic treatment JP实验室股份有限公司 2026-05-19 CN disclosed
US-20020192247-A1 Thermochromic/photochromic cosmetic compositions THEISEN LYLE (US) 2002-12-19 US disclosed
EP-1057653-A1 Method of producing color changes I.P.T. - Impression Printing Technologies B.V. (NL) 2000-12-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050203067-A1 Pesticidal compositions and methods ACHE, DDT, PTMS TDP1 2337/4885ALDH1A1 3205/4885MAPK1 4785/4885
US-20080244837-A1 Cosmetic article and process for dry dyeing keratin materials KRT18, CUTA, DSG1 TDP1 3293/4885ALDH1A1 844/4885MAPK1 1820/4885
US-20080148496-A1 Dyeing of in Particular Human Keratin Materials by Dry Thermal Transfer of a Direct Dye, Composition Comprising the Said Dye and Its Method of Preparation KRT18, IK, DSG1 TDP1 3318/4885ALDH1A1 911/4885MAPK1 2433/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.