Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.50 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.50 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 3/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.49 |
| ▸ | PPARD | Q03181 | 2/20 | 0.49 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.47 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.45 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7341170 | 0.89 | PYGL (0.58) | PYGLKDM4EPDK1PDK2PDK3 | |
| SCHEMBL8314728 | 0.80 | PYGL (0.62) | PYGLKDM4EPDK1PDK2PDK3 | |
| SCHEMBL8314210 | 0.78 | PYGL (0.64) | PYGLKDM4EPDK1PDK2PDK3 | |
| SCHEMBL16147800 | 0.77 | TMPRSS4 (0.59) | PYGLPDK1PDK2PDK3PDK4 | |
| SCHEMBL27532598 | 0.77 | MEN1 (0.59) | PDK1PDK2PDK3PDK4PPARG | |
| SCHEMBL8316647 | 0.76 | PYGL (0.54) | PYGLKDM4EPDK1PDK2PDK3 | |
| SCHEMBL16147472 | 0.75 | NR1H4 (0.52) | PYGLKDM4EPDK1PDK2PDK3 | |
| SCHEMBL8313578 | 0.75 | PYGL (0.56) | PYGLKDM4EPDK1PDK2PDK3 | |
| SCHEMBL20601791 | 0.75 | KCNK3 (0.55) | KDM4EPPARGNR1H4KCNK3KCNK9 | |
| SCHEMBL31585855 | 0.75 | KCNK3 (0.55) | KDM4EPPARGNR1H4KCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014165816-A1 | COMPOUNDS USEFUL FOR THE TREATMENT OF METABOLIC DISORDERS AND SYNTHESIS OF THE SAME | NORTH CAROLINA CENTRAL UNIVERSITY (US) | 2014-10-09 | — | — | WO | disclosed |