Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 4/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.48 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8313578 | 0.82 | PYGL (0.56) | PYGLRAB9ATSHRMAPTNPC1 | |
| SCHEMBL7332090 | 0.82 | PYGL (0.62) | PYGLRAB9AHPGDMEN1KMT2A | |
| SCHEMBL16148003 | 0.81 | PYGL (0.55) | PYGLRAB9AHPGDCYP1A2CYP2C19 | |
| SCHEMBL8317200 | 0.81 | RAB9A (0.54) | RAB9ACYP1A2MEN1KMT2AMAPT | |
| SCHEMBL8316647 | 0.80 | PYGL (0.54) | PYGLRAB9AKMT2AMAPTNPC1 | |
| SCHEMBL7341170 | 0.79 | PYGL (0.58) | PYGLRAB9ACYP1A2CYP2C19MEN1 | |
| SCHEMBL16160868 | 0.79 | PYGL (0.55) | PYGLRAB9AMEN1KMT2AMAPT | |
| SCHEMBL16147803 | 0.78 | PYGL (0.52) | PYGLRAB9ACYP1A2CYP2C19P2RX7 | |
| SCHEMBL6968515 | 0.78 | PYGL (0.57) | PYGLRAB9AMEN1KMT2AMAPT | |
| SCHEMBL16147659 | 0.77 | NPC1 (0.56) | PYGLRAB9AMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636625-B1 | Tricyclic diazepines vasopressin and oxytocin antagonists | AMERICAN CYANAMID CO (US) | 1999-01-27 | — | — | EP | disclosed |