Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 7/20 | 0.54 |
| ▸ | ERBB2 | P04626 | 6/20 | 0.54 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.48 |
| ▸ | PTP4A2 | Q12974 | 1/20 | 0.48 |
| ▸ | PTP4A1 | Q93096 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16148661 | 1.00 | EGFR (0.54) | EGFRERBB2DNM1KMT2AMEN1 | |
| SCHEMBL8749247 | 0.86 | DNM1 (0.61) | EGFRERBB2DNM1KMT2AMEN1 | |
| SCHEMBL5164387 | 0.86 | DNM1 (0.61) | EGFRERBB2DNM1KMT2AMEN1 | |
| SCHEMBL16160400 | 0.85 | ALDH1A1 (0.62) | EGFRERBB2DNM1KMT2AMEN1 | |
| SCHEMBL7820539 | 0.83 | DNM1 (0.70) | EGFRERBB2DNM1KMT2AMEN1 | |
| SCHEMBL7820542 | 0.83 | DNM1 (0.70) | EGFRERBB2DNM1KMT2AMEN1 | |
| SCHEMBL8646383 | 0.77 | KDM4E (0.56) | DNM1KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL11761701 | 0.77 | KDM4E (0.56) | DNM1KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL9559164 | 0.77 | EGFR (0.56) | EGFRERBB2DNM1KMT2AMEN1 | |
| SCHEMBL29813583 | 0.76 | EGFR (0.73) | EGFRDNM1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014164667-A1 | DENGUE AND WEST NILE VIRUS PROTEASE INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2014-10-09 | — | — | WO | disclosed |