SCHEMBL1614877

SCHEMBL1614877

CCCCOC(=O)/C=C/c1ccccc1OC

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.73
ALDH1A1 P00352 4/20 0.73
HPGD P15428 3/20 0.69
SMN1; SMN2 Q16637 1/20 0.69
NFE2L2 Q16236 2/20 0.60
TFEB P19484 1/20 0.59
AKR1B10 O60218 5/20 0.57
AKR1B1 P15121 5/20 0.57
MAPT P10636 3/20 0.56
KMT2A Q03164 2/20 0.56
MEN1 O00255 1/20 0.54
NPC1 O15118 2/20 0.54
RAB9A P51151 2/20 0.54
LMNA P02545 1/20 0.54
BCHE P06276 1/20 0.54
MAOB P27338 1/20 0.53
MAPK1 P28482 1/20 0.52
ATM Q13315 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
TDP1 Q9NUW8 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19244312 1.00 KDM4E (0.73) KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2
SCHEMBL5177689 0.97 KDM4E (0.73) KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2
SCHEMBL8872224 0.96 KDM4E (0.71) KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2
SCHEMBL466048 0.96 KDM4E (0.71) KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2
SCHEMBL4421062 0.96 KDM4E (0.71) KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2
SCHEMBL8872479 0.96 KDM4E (0.71) KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2
SCHEMBL4629237 0.96 KDM4E (0.71) KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2
Hydrochloric Acid SCHEMBL10437236 0.95 KDM4E (0.73) KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2
SCHEMBL19244396 0.92 KDM4E (0.61) KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2
SCHEMBL2474892 0.92 KDM4E (0.72) KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3348251-B1 SUNSCREEN COMPOSITIONS GLAXOSMITHKLINE CONSUMER HEALTHCARE HOLDINGS US LLC (US) 2024-01-17 EP disclosed
WO-2023194511-A1 COMPOSITION FOR THE COSMETIC TREATMENT OF KERATIN FIBERS BIOSYNTHIS (FR) 2023-10-12 WO disclosed
EP-3953407-A1 TWO-COMPONENT POLYURETHANE COATINGS HAVING IMPROVED POT LIFE WITHOUT A LOSS OF WEATHERING RESISTANCE Covestro Intellectual Property GmbH & Co. KG (DE) 2022-02-16 EP disclosed
EP-3797756-A1 SUNSCREEN AGENT USING CELLULOSE NANOFIBERS Nature Costech Co., Ltd. (KR) 2021-03-31 EP disclosed
WO-2020207898-A1 TWO-COMPONENT POLYURETHANE COATINGS HAVING IMPROVED POT LIFE WITHOUT A LOSS OF WEATHERING RESISTANCE COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2020-10-15 WO disclosed
EP-3208301-B1 RESIN COMPOSITION AND OPTICAL COMPENSATION FILM USING SAME TOSOH CORP (JP) 2019-04-03 EP disclosed
US-10126478-B2 Resin composition and optical compensation film using same TOSOH CORPORATION (JP) 2018-11-13 US disclosed
EP-3348251-A1 SUNSCREEN COMPOSITIONS Wyeth LLC (US) 2018-07-18 EP disclosed
EP-2488151-B1 SUNSCREEN COMPOSITIONS WYETH LLC (US) 2018-02-28 EP disclosed
US-20170242174-A1 RESIN COMPOSITION AND OPTICAL COMPENSATION FILM USING SAME TOSOH CORPORATION (JP) 2017-08-24 US disclosed
EP-1434562-B1 COSMETIC AND DERMATOLOGICAL STICK BEIERSDORF AG (DE) 2017-08-16 EP disclosed
US-9399008-B2 Sunscreen compositions WYETH LLC (US) 2016-07-26 US disclosed
US-20150305996-A1 SUNSCREEN COMPOSITIONS CONOPCO, INC. 2015-10-29 US disclosed
US-9126059-B2 Sunscreen compositions WYETH LLC (US) 2015-09-08 US disclosed
US-8329200-B2 Water in oil emulsion has moisturizer of glycerol, chitosan, Fucogel, propylene glycol, polyoxyethylene glycol, dipropylene glycol, butylene glycol, mannitol, lactic acid, glycine,, sodium 2-pyrrolidone-5-carboxylate, hyaluronic acid, urea, and/or salts; storage stability; acne, wrinkle resistance BEIERSDORF AG (DE) 2012-12-11 US disclosed
EP-2488151-A2 SUNSCREEN COMPOSITIONS Wyeth LLC (US) 2012-08-22 EP disclosed
WO-2011046919-A2 SUNSCREEN COMPOSITIONS WYETH LLC (US) 2011-04-21 WO disclosed
US-20110085994-A1 Sunscreen Compositions WYETH LLC (US) 2011-04-14 US disclosed
US-7465438-B2 Solubilizing agents/solvents for organic UV filters GOLDSCHMIDT GMBH (DE) 2008-12-16 US disclosed
US-20050232877-A1 Solubilizing agents/solvents for organic UV filters GOLDSCHMIDT GMBH (DE) 2005-10-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050232877-A1 Solubilizing agents/solvents for organic UV filters APP, BACE1, CBR1 KDM4E 2681/4885ALDH1A1 343/4885HPGD 770/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.