Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3285647 | 0.91 | SIGMAR1 (0.39) | SIGMAR1HCAR2TRPM8DRD2HTR2A | |
| SCHEMBL1246125 | 0.74 | SIGMAR1 (0.44) | SIGMAR1HCAR2TRPM8DRD2HTR2A | |
| SCHEMBL27703890 | 0.74 | SIGMAR1 (0.38) | SIGMAR1TRPM8DRD2HTR2AEPHX2 | |
| SCHEMBL3653997 | 0.73 | ADAMTS4 (0.31) | HTR2ATDP1ADAMTS4ALDH1A1EGFR | |
| SCHEMBL28400798 | 0.73 | SIGMAR1 (0.43) | SIGMAR1HCAR2TRPM8DRD2HTR2A | |
| SCHEMBL2967626 | 0.73 | MEN1 (0.40) | SIGMAR1DRD2ALDH1A1CA2LMNA | |
| SCHEMBL6864752 | 0.72 | MEN1 (0.43) | SIGMAR1DRD2ALDH1A1CA2LMNA | |
| SCHEMBL28965834 | 0.72 | GAA (0.34) | SIGMAR1HCAR2TRPM8DRD2HTR2A | |
| Methyl Alcohol SCHEMBL28796336 | 0.72 | SIGMAR1 (0.42) | SIGMAR1TRPM8DRD2HTR2AEPHX2 | |
| SCHEMBL7919904 | 0.72 | HCAR2 (0.43) | SIGMAR1HCAR2TRPM8DRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2981260-A2 | NOVEL ANALOGUES OF EPICATECHIN AND RELATED POLYPHENOLS | Sphaera Pharma Pvt. Ltd. (IN) | 2016-02-10 | — | — | EP | disclosed |
| WO-2014162320-A2 | NOVEL ANALOGUES OF EPICATECHIN AND RELATED POLYPHENOLS | SPHAERA PHARMA PVT. LTD. (IN) | 2014-10-09 | — | — | WO | disclosed |