SCHEMBL1615124

SCHEMBL1615124

CCCOc1c(Cl)cc(Cl)c2c1[S+]([O-])c1ccccc1C2

nearest known ligand 0.32

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
HTT P42858 1/20 0.32
KMT2A Q03164 1/20 0.32
PTPRC P08575 4/20 0.32
PTPN2 P17706 4/20 0.32
PTPN1 P18031 4/20 0.32
PTPRB P23467 4/20 0.32
PTPN11 Q06124 4/20 0.32
GSTA1 P08263 2/20 0.32
GSTP1 P09211 2/20 0.32
DRD2 P14416 1/20 0.32
DRD1 P21728 1/20 0.32
DRD5 P21918 1/20 0.32
DRD3 P35462 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1614168 0.91 PTPRC (0.32) PTPRCPTPN2PTPN1PTPRBPTPN11
SCHEMBL3163402 0.83 THRB (0.34) PTPN1GSTA1GSTP1
SCHEMBL133173 0.82 CSNK2A1 (0.35) MEN1MAPTKMT2A
SCHEMBL7259160 0.81 L3MBTL1 (0.32) PTPRCPTPN2PTPN1PTPRBPTPN11
SCHEMBL1614823 0.77 MAPT (0.31) MAPT
SCHEMBL3162888 0.75 PTPN1 (0.39) MEN1MAPTHPGDKMT2APTPN1
SCHEMBL1195776 0.75 MAPT (0.35) MAPTPTPRCPTPN2PTPN1PTPRB
SCHEMBL3159501 0.74 S1PR5 (0.36) MEN1MAPTHPGDKMT2APTPN1
SCHEMBL1615176 0.74 S1PR5 (0.36) MEN1MAPTHPGDKMT2APTPN1
SCHEMBL7769310 0.73 PTPRC (0.30) PTPRCPTPN2PTPN1PTPRBPTPN11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110086314-A1 MELTS ROHM AND HAAS ELECTRONIC MATERIAL LLC (US) 2011-04-14 US disclosed
EP-0520574-B1 Thioxanthone derivatives LAMBSON FINE CHEMICALS LIMITED (GB) 2000-08-16 EP disclosed
US-5414092-A Photoinitiators INTERNATIONAL BIO-SYNTHETICS LIMITED (GB) 1995-05-09 US disclosed
EP-0520574-A1 Thioxanthone derivatives GREAT LAKES FINE CHEMICALS LIMITED (GB) 1992-12-30 EP disclosed