Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL804728 | 0.96 | TSHR (0.38) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL1636800 | 0.94 | TSHR (0.32) | TSHR | |
| SCHEMBL804365 | 0.94 | MEN1 (0.38) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL16260481 | 0.92 | TSHR (0.31) | TSHR | |
| SCHEMBL804359 | 0.91 | TSHR (0.33) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL14700556 | 0.91 | TSHR (0.33) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL17716670 | 0.90 | TSHR (0.54) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL13251278 | 0.87 | TSHR (0.35) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL15384646 | 0.86 | TSHR (0.30) | TSHR | |
| SCHEMBL3890845 | 0.84 | TSHR (0.34) | TSHRMEN1THRBHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9921340-B2 | Water-processable silicone-containing prepolymers and uses thereof | NOVARTIS AG (CH) | 2018-03-20 | — | — | US | disclosed |
| US-20160033683-A1 | WATER-PROCESSABLE SILICONE-CONTAINING PREPOLYMERS AND USES THEREOF | ALCON INC. (CH) | 2016-02-04 | — | — | US | disclosed |
| US-9187601-B2 | Water-processable silicone-containing prepolymers and uses thereof | NOVARTIS AG (CH) | 2015-11-17 | — | — | US | disclosed |
| US-20120088861-A1 | WATER-PROCESSABLE SILICONE-CONTAINING PREPOLYMERS AND USES THEREOF | ALCON INC. (CH) | 2012-04-12 | — | — | US | disclosed |