Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1615256 | 0.92 | TSHR (0.36) | TSHR | |
| SCHEMBL804728 | 0.88 | TSHR (0.38) | TSHR | |
| SCHEMBL804365 | 0.86 | MEN1 (0.38) | TSHR | |
| SCHEMBL1636800 | 0.86 | TSHR (0.32) | TSHR | |
| SCHEMBL14700556 | 0.83 | TSHR (0.33) | TSHR | |
| SCHEMBL804359 | 0.83 | TSHR (0.33) | TSHR | |
| SCHEMBL12937831 | 0.83 | — | — | |
| SCHEMBL17716670 | 0.82 | TSHR (0.54) | TSHR | |
| SCHEMBL13251278 | 0.80 | TSHR (0.35) | TSHR | |
| SCHEMBL15384646 | 0.78 | TSHR (0.30) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9052440-B2 | Chain-extended polysiloxane crosslinkers with dangling hydrophilic polymer chains | NOVARTIS AG (CH) | 2015-06-09 | — | — | US | disclosed |
| US-20140350124-A1 | CHAIN-EXTENDED POLYSILOXANE CROSSLINKERS WITH DANGLING HYDROPHILIC POLYMER CHAINS | ALCON INC. (CH) | 2014-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140350124-A1 | CHAIN-EXTENDED POLYSILOXANE CROSSLINKERS WITH DANGLING HYDROPHILIC POLYMER CHAINS | HACD2, HACD3, PCNA | TSHR 4087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.