Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.31 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15297869 | 0.93 | TSHR (0.50) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL18961414 | 0.93 | TSHR (0.50) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL47736 | 0.92 | TSHR (0.59) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL2406752 | 0.92 | TSHR (0.50) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL15293381 | 0.91 | TSHR (0.57) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL1615256 | 0.90 | TSHR (0.36) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL10331158 | 0.87 | TSHR (0.57) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL804728 | 0.86 | TSHR (0.38) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL18858129 | 0.85 | MEN1 (0.43) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL10030114 | 0.85 | TSHR (0.55) | TSHRMEN1KMT2ATHRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160121101-A1 | Medical leads | MEDTRONIC, INC. | 2016-05-05 | — | — | US | disclosed |