Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4437792 | 0.93 | GSTP1 (0.59) | GSTP1MAPTMEN1KMT2AUSP2 | |
| SCHEMBL31343967 | 0.85 | GSTP1 (0.58) | GSTP1MAPTMEN1KMT2AUSP2 | |
| SCHEMBL17970190 | 0.82 | KMT2A (0.66) | GSTP1MAPTMEN1KMT2AUSP2 | |
| SCHEMBL22434379 | 0.80 | MEN1 (0.62) | GSTP1MAPTMEN1KMT2AUSP2 | |
| SCHEMBL13435046 | 0.79 | KMT2A (0.53) | GSTP1MAPTMEN1KMT2AUSP2 | |
| SCHEMBL22197942 | 0.78 | FTO (0.53) | MAPTMEN1KMT2AHTTKCNH2 | |
| SCHEMBL29388062 | 0.78 | MEN1 (0.59) | GSTP1MAPTMEN1KMT2AUSP2 | |
| SCHEMBL19431854 | 0.77 | GSTP1 (0.47) | GSTP1MAPTMEN1KMT2AUSP2 | |
| SCHEMBL23599906 | 0.75 | FTO (0.51) | MAPTMEN1KMT2AHTTKCNH2 | |
| SCHEMBL19607558 | 0.75 | KCNH2 (0.47) | GSTP1MAPTMEN1KMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1782071-B1 | COVALENT TETHERING OF FUNCTIONAL GROUPS TO PROTEINS AND SUBSTRATES THEREFOR | PROMEGA CORP (US) | 2014-10-08 | — | — | EP | disclosed |