Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.47 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.47 |
| ▸ | NDUFS8 | O00217 | 1/20 | 0.44 |
| ▸ | COXFA4 | O00483 | 1/20 | 0.44 |
| ▸ | NDUFAB1 | O14561 | 1/20 | 0.44 |
| ▸ | NDUFA1 | O15239 | 1/20 | 0.44 |
| ▸ | NDUFS4 | O43181 | 1/20 | 0.44 |
| ▸ | NDUFB5 | O43674 | 1/20 | 0.44 |
| ▸ | NDUFB3 | O43676 | 1/20 | 0.44 |
| ▸ | NDUFC1 | O43677 | 1/20 | 0.44 |
| ▸ | NDUFA2 | O43678 | 1/20 | 0.44 |
| ▸ | NDUFS5 | O43920 | 1/20 | 0.44 |
| ▸ | NDUFS7 | O75251 | 1/20 | 0.44 |
| ▸ | NDUFS2 | O75306 | 1/20 | 0.44 |
| ▸ | NDUFS6 | O75380 | 1/20 | 0.44 |
| ▸ | NDUFB1 | O75438 | 1/20 | 0.44 |
| ▸ | NDUFS3 | O75489 | 1/20 | 0.44 |
| ▸ | NDUFB6 | O95139 | 1/20 | 0.44 |
| ▸ | NDUFA3 | O95167 | 1/20 | 0.44 |
| ▸ | NDUFB4 | O95168 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29405405 | 0.77 | ALB (0.58) | KCNH2GSTP1MAPTMEN1KMT2A | |
| SCHEMBL17970190 | 0.75 | KMT2A (0.66) | KCNH2GSTP1MAPTMEN1KMT2A | |
| SCHEMBL16153115 | 0.75 | GSTP1 (0.55) | KCNH2GSTP1MAPTMEN1KMT2A | |
| SCHEMBL4437792 | 0.75 | GSTP1 (0.59) | KCNH2GSTP1MAPTMEN1KMT2A | |
| SCHEMBL15298989 | 0.74 | ALB (0.50) | KCNH2GSTP1MAPTMEN1KMT2A | |
| SCHEMBL22434379 | 0.73 | MEN1 (0.62) | KCNH2GSTP1MAPTMEN1KMT2A | |
| SCHEMBL17956704 | 0.70 | FTO (0.60) | KCNH2GSTP1MAPTMEN1KMT2A | |
| SCHEMBL13237871 | 0.69 | GSTP1 (0.49) | KCNH2GSTP1MAPTMEN1KMT2A | |
| SCHEMBL15298990 | 0.69 | ALB (0.46) | KCNH2GSTP1MAPTMEN1KMT2A | |
| SCHEMBL31343967 | 0.69 | GSTP1 (0.58) | KCNH2GSTP1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170327633-A1 | COMPOSITIONS AND METHODS OF MAKING POLYMERIZING NUCLEIC ACIDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170327633-A1 | COMPOSITIONS AND METHODS OF MAKING POLYMERIZING NUCLEIC ACIDS | RNGTT, NSUN2, POLN | KCNH2 4664/4885GSTP1 4351/4885NDUFS8 3300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.