SCHEMBL1615508

SCHEMBL1615508

CCO[Si](CCOC(=O)CCCCCC(C)(C)C)(OCC)OCC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.45
DNM1 Q05193 1/20 0.39
GAA P10253 1/20 0.37
PAM P19021 2/20 0.35
PRSS1 P07477 1/20 0.35
PRSS2 P07478 1/20 0.35
PRSS3 P35030 1/20 0.35
CYP1A2 P05177 1/20 0.34
EPHX2 P34913 5/20 0.33
TSHR P16473 2/20 0.33
ALDH1A1 P00352 2/20 0.33
CYP4F2 P78329 1/20 0.33
CYP4A11 Q02928 1/20 0.33
CYP3A4 P08684 1/20 0.33
ALOX15 P16050 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
MAPT P10636 1/20 0.33
CNR2 P34972 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22030780 0.79 DGKA (0.60) DGKADNM1PAMPRSS1PRSS2
SCHEMBL15183505 0.79 CYP1A2 (0.53) DGKAGAAPAMCYP1A2TSHR
SCHEMBL10250453 0.79 CYP1A2 (0.53) DGKAGAAPAMCYP1A2TSHR
SCHEMBL15183507 0.79 CYP1A2 (0.53) DGKAGAAPAMCYP1A2TSHR
SCHEMBL12933282 0.79 CYP1A2 (0.53) DGKAGAAPAMCYP1A2TSHR
SCHEMBL15183506 0.79 CYP1A2 (0.53) DGKAGAAPAMCYP1A2TSHR
SCHEMBL4467504 0.78 DGKA (0.42) DGKADNM1GAAPAMPRSS1
SCHEMBL10250444 0.78 DGKA (0.63) DGKADNM1PAMPRSS1PRSS2
SCHEMBL2933813 0.78 DGKA (0.63) DGKADNM1PAMPRSS1PRSS2
SCHEMBL1908800 0.77 CYP1A2 (0.55) DGKAGAAPAMCYP1A2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9006373-B2 Photo-patternable dielectric materials curable to porous dielectric materials, formulations, precursors and methods of use thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2015-04-14 US disclosed
US-8981031-B2 Photo-patternable dielectric materials curable to porous dielectric materials, formulations, precursors and methods of use thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2015-03-17 US disclosed
US-8946371-B2 Photo-patternable dielectric materials curable to porous dielectric materials, formulations, precursors and methods of use thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2015-02-03 US disclosed
US-20130207278-A1 PHOTO-PATTERNABLE DIELECTRIC MATERIALS CURABLE TO POROUS DIELECTRIC MATERIALS, FORMULATIONS, PRECURSORS AND METHODS OF USE THEREOF INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-08-15 US disclosed
US-20130197253-A1 PHOTO-PATTERNABLE DIELECTRIC MATERIALS CURABLE TO POROUS DIELECTRIC MATERIALS, FORMULATIONS, PRECURSORS AND METHODS OF USE THEREOF INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-08-01 US disclosed
US-20130189836-A1 PHOTO-PATTERNABLE DIELECTRIC MATERIALS CURABLE TO POROUS DIELECTRIC MATERIALS, FORMULATIONS, PRECURSORS AND METHODS OF USE THEREOF INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-07-25 US disclosed
US-8389663-B2 Photo-patternable dielectric materials curable to porous dielectric materials, formulations, precursors and methods of use thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-03-05 US disclosed
US-20110083887-A1 PHOTO-PATTERNABLE DIELECTRIC MATERIALS CURABLE TO POROUS DIELECTRIC MATERIALS, FORMULATIONS, PRECURSORS AND METHODS OF USE THEREOF INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2011-04-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110083887-A1 PHOTO-PATTERNABLE DIELECTRIC MATERIALS CURABLE TO POROUS DIELECTRIC MATERIALS, FORMULATIONS, PRECURSORS AND METHODS OF USE THEREOF PTGIS, KDM2A, PTGES DGKA 3645/4885DNM1 3359/4885GAA 2783/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.