SCHEMBL161552

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL162580	0.86	HPGD (0.46)	KMT2AL3MBTL1NPC1HPGDTP53
	SCHEMBL164518	0.83	TSHR (0.56)	L3MBTL1LMNAHPGDCA2CA4
	SCHEMBL163649	0.82	HTT (0.46)	KMT2ALMNANPC1HPGDTP53
	SCHEMBL163608	0.81	SLC6A2 (0.37)	LMNAHDAC6NPC1HPGDALDH1A1
	SCHEMBL161414	0.78	MEN1 (0.50)	KMT2AL3MBTL1LMNANPC1HPGD
	SCHEMBL166717	0.78	POLB (0.41)	KMT2AL3MBTL1LMNAHPGDALDH1A1
	SCHEMBL161119	0.76	ALOX5 (0.39)	NPC1HPGDTP53FUCA1ALDH1A1
	SCHEMBL162070	0.76	—	—
	SCHEMBL164391	0.73	MAPT (0.39)	KMT2ALMNAHPGDCA2ALDH1A1
	SCHEMBL162511	0.73	TSHR (0.48)	KMT2AL3MBTL1LMNANPC1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.