Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | GPR39 | O43194 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13858509 | 0.88 | CHRNA7 (0.42) | RAB9ANPC1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL13858557 | 0.81 | HPGD (0.44) | RAB9ANPC1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL13720913 | 0.80 | ALDH1A1 (0.46) | RAB9ANPC1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL1788511 | 0.79 | ALDH1A1 (0.47) | RAB9ANPC1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL30795479 | 0.79 | ALDH1A1 (0.47) | RAB9ANPC1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL16156008 | 0.78 | OGFRL1 (0.42) | ALDH1A1SMN1; SMN2LMNATSHRHTT | |
| SCHEMBL16156007 | 0.78 | OGFRL1 (0.42) | ALDH1A1SMN1; SMN2LMNATSHRHTT | |
| SCHEMBL30795801 | 0.76 | ALDH1A1 (0.50) | RAB9ANPC1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL1786371 | 0.76 | ALDH1A1 (0.50) | RAB9ANPC1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL1791098 | 0.76 | ALDH1A1 (0.45) | RAB9ANPC1ALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8859549-B2 | Potassium channel modulators | ABBVIE, INC. (US) | 2014-10-14 | — | — | US | claimed |
| US-8859549-B2 | Potassium channel modulators | ABBVIE, INC. (US) | 2014-10-14 | — | — | US | disclosed |