SCHEMBL1615740

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1616399	0.88	HDAC6 (0.43)	SYKGBA1DDB1CRBNHDAC6
	SCHEMBL1616700	0.84	CDK1 (0.44)	GBA1DDB1CRBNHDAC6KCNN3
	SCHEMBL1616741	0.83	CDK1 (0.42)	GBA1HDAC6KCNN3JAK2JAK1
	SCHEMBL3844986	0.80	PDPK1 (0.47)	GBA1DDB1CRBNHDAC6KCNN3
	SCHEMBL1616678	0.79	FADS1 (0.47)	GBA1HDAC6KCNN3JAK2JAK1
	SCHEMBL1615579	0.79	PFKFB3 (0.42)	GBA1HDAC6KCNN3FADS1PFKFB3
	SCHEMBL1616344	0.78	GBA1 (0.46)	GBA1DDB1CRBNHDAC6KCNN3
	SCHEMBL1616343	0.78	GBA1 (0.46)	GBA1DDB1CRBNHDAC6KCNN3
	SCHEMBL2245619	0.77	GBA1 (0.47)	GBA1DDB1CRBNHDAC6KCNN3
	SCHEMBL1616633	0.77	HDAC6 (0.43)	GBA1DDB1CRBNHDAC6KCNN3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.