SCHEMBL1616741

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1616700	0.94	CDK1 (0.44)	CDK1FADS1HDAC6KCNN3EGFR
	SCHEMBL1616399	0.87	HDAC6 (0.43)	CDK1FADS1HDAC6KCNN3GBA1
	SCHEMBL1615740	0.83	SYK (0.39)	CDK1FADS1HDAC6KCNN3EGFR
	SCHEMBL1615579	0.82	PFKFB3 (0.42)	FADS1HDAC6KCNN3GBA1PFKFB3
	SCHEMBL1616678	0.82	FADS1 (0.47)	CDK1FADS1HDAC6KCNN3GBA1
	SCHEMBL1616631	0.78	HDAC6 (0.43)	CDK1FADS1HDAC6KCNN3GBA1
	SCHEMBL1616633	0.78	HDAC6 (0.43)	CDK1FADS1HDAC6KCNN3GBA1
	SCHEMBL1616386	0.78	GBA1 (0.41)	CDK1FADS1HDAC6KCNN3EGFR
	SCHEMBL1616104	0.78	HDAC6 (0.38)	FADS1HDAC6KCNN3GBA1TRPV1
	SCHEMBL3844986	0.77	PDPK1 (0.47)	FADS1HDAC6KCNN3EGFRGBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.