SCHEMBL16158397

SCHEMBL16158397

Nc1ccc2c(c1)-c1ccccc1C2c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK5 Q00535 2/20 0.50
CHEK1 O14757 1/20 0.50
AURKA O14965 1/20 0.50
DAPK3 O43293 1/20 0.50
JAK2 O60674 1/20 0.50
PRKD3 O94806 1/20 0.50
MAP4K4 O95819 1/20 0.50
PAK4 O96013 1/20 0.50
ABL1 P00519 1/20 0.50
NTRK1 P04629 1/20 0.50
LCK P06239 1/20 0.50
FYN P06241 1/20 0.50
CSF1R P07333 1/20 0.50
RET P07949 1/20 0.50
IGF1R P08069 1/20 0.50
MET P08581 1/20 0.50
PDGFRB P09619 1/20 0.50
PIM1 P11309 1/20 0.50
FGFR1 P11362 1/20 0.50
PDGFRA P16234 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29601950 0.89 CDK5 (0.54) CDK5CHEK1AURKADAPK3JAK2
SCHEMBL6138419 0.84 CYP3A4 (0.44) CDK5CHEK1AURKADAPK3JAK2
SCHEMBL25171318 0.83 LMNA (0.54) CDK5CHEK1AURKADAPK3JAK2
SCHEMBL29370508 0.83 LMNA (0.54) CDK5CHEK1AURKADAPK3JAK2
SCHEMBL70993 0.83 LMNA (0.54) CDK5CHEK1AURKADAPK3JAK2
Benzene SCHEMBL27791155 0.83 LMNA (0.54) CDK5CHEK1AURKADAPK3JAK2
SCHEMBL1681655 0.81 HTR2A (0.43) CDK5CHEK1AURKADAPK3JAK2
SCHEMBL9803785 0.81 CDK5 (0.40) CDK5CHEK1AURKADAPK3JAK2
SCHEMBL10042990 0.79 CYP1A2 (0.50) NPC1CYP3A4TP53MAPK1TDP1
SCHEMBL28851605 0.79 HTR2A (0.44) ALDH1A1CYP3A4TP53MAPK1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4016656-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND Samsung Electronics Co., Ltd. (KR) 2022-06-22 EP disclosed
WO-2014163228-A1 NOVEL ORGANIC ELECTROLUMINESCENT ELEMENT COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME (주)피엔에이치테크 (KR) 2014-10-09 WO disclosed